Virulence traits-based behavior of Streptococcus mutans bacteria from dental plaque and dental caries conditions

Bakr, Rana Abo; Tawfick, Mahmoud M.; Mostafa, Zeinab; Abdulall, Abeer K.

doi:10.21608/mb.2021.100068.1044

MBJ

2021

DOI: 10.21608/mb.2021.100068.1044

|View full text |Cite

Virulence traits-based behavior of Streptococcus mutans bacteria from dental plaque and dental caries conditions

Rana Abo Bakr

Mahmoud M. Tawfick

Zeinab Mostafa

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Comparison of the Effect of Fluoride 0.2% and a Combined Mouthwash (Flavonoid Compounds and Fluoride 0.2%) Against Streptococcus mutans and Lactobacillus acidophilus: In Silico and In Vitro Study

Omidi,

SarveAhrabi,

Nejati Khoei

2023

Avicenna J Dent Res

View full text Add to dashboard Cite

Background: Tooth decay is one of the most common health problems in the world. Nowadays, finding new compounds to prevent tooth decay is more necessary than ever. The purpose of this study was to compare the effects of fluoride 0.2% and mouthwash combined with flavonoid compounds against bacterial samples. Methods: The crystal structures of glucansucrase from Streptococcus mutans and glucan-1, 6-alpha-glucosidase from Lactobacillus acidophilus were obtained from the Protein Data Bank. By using AutoDockTools (1.5.7), ligands and protein interactions were calculated and ready for AutoDock vina. The agar well diffusion and the minimum inhibitory concentration/minimum bactericidal concentration (MIC/MBC) methods were used to investigate the inhibitory effect of mouthwashes, and the results were obtained with SPSS software. Results: Compounds eriocitrin and galangin showed the highest amount of H-bonds with amino acids against glucansucrase. In addition, catechin, eriocitrin, and isorhamnetin compounds demonstrated the highest amount of H-bonds with amino acids against glucan-1, 6-alpha-glucosidase. In vitro results revealed that groups a (Fluoride 0.2%+eriocitrin against S. mutans) and d (Fluoride 0.2%+eriocitrin against L. acidophilus) represented the most effect among all compounds, respectively (Inhibition zone=26±0.5 mm, MIC=250 µg/mL, MBC=500 µg/mL and inhibition zone=31±0.5 mm, MIC=125 µg/mL, MBC=250 µg/mL). Conclusion: Fluoride 0.2% with eriocitrin was more effective in both methods (In silico and in vitro) compared to fluoride 0.2% due to its good inhibitory effect at different concentrations against S. mutans and L. acidophilus.

show abstract

Comparison of the Effect of Fluoride 0.2% and a Combined Mouthwash (Flavonoid Compounds and Fluoride 0.2%) Against Streptococcus mutans and Lactobacillus acidophilus: In Silico and In Vitro Study

Omidi,

SarveAhrabi,

Nejati Khoei

2023

Avicenna J Dent Res

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Virulence traits-based behavior of Streptococcus mutans bacteria from dental plaque and dental caries conditions

Cited by 1 publication

References 43 publications

Comparison of the Effect of Fluoride 0.2% and a Combined Mouthwash (Flavonoid Compounds and Fluoride 0.2%) Against Streptococcus mutans and Lactobacillus acidophilus: In Silico and In Vitro Study

Comparison of the Effect of Fluoride 0.2% and a Combined Mouthwash (Flavonoid Compounds and Fluoride 0.2%) Against Streptococcus mutans and Lactobacillus acidophilus: In Silico and In Vitro Study

Contact Info

Product

Resources

About