Virus Infections

Sterling, Jane

doi:10.1002/9780470750520.ch25

Cited by 59 publications

(121 citation statements)

References 764 publications

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“…HPV 16 is a mucosal HPV type with preference for genital areas, and HPV 11, also mucosal, presents replication in laryngeal and genital epithelium. 11 This classification is not entirely correct, because genital HPV types can be detected in the skin and the opposite is also possible.…”

Section: Alpha-papillomavirus (Supergroup A)mentioning

confidence: 99%

“…The diagnosis of HPV infection is made by histopathology of lesions 11 or detection of viral DNA in infected cells. 12 Hybridization techniques and polymerase chain reaction (PCR) are methods used for HPV detection.…”

Section: Techniques For Detection Of Hpvmentioning

confidence: 99%

“…A higher prevalence of warts and longer and persistent manifestations are observed in patients with CMI suppression, such as in kidney-transplant recipients, individuals with HIV (human immunodeficiency virus), and patients with EV. 5,11,17 The life cycle of an HPV is directly linked to the cell differentiation program of the host cell. Infection begins when the HPV reaches the cells of the basal layer; there is no viral replication at this location and the virus just keeps its genome by amplification of a low number of copies.…”

Section: Epidemiology Transmission and Pathogenesismentioning

confidence: 99%

“…17 A frequent location in children is the knee. 11 Isolated warts may remain unaltered for months or years, or a large number of new lesions may develop rapidly in a short period of time. The development of warts is not predictable.…”

Section: Common Wartsmentioning

confidence: 99%

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Infecção pelo papilomavírus humano: etiopatogenia, biologia molecular e manifestações clínicas

Leto¹,

Júnior²,

Porro

et al. 2011

An. Bras. Dermatol.

113

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Human papillomavirus (HPV) is a DNA virus that presents tropism for epithelial cells, causing infections of the skin and mucous membranes. Replication of HPV occurs in the nuclei of squamous cells and its life cycle is directly related to the differentiation program of the host cell. To date, nearly 100 different types of HPV have been characterized and there is a large number of other types that have not been sequenced yet. Besides being responsible for benign lesions of the skin and mucous membranes, HPV is also involved in the development of various mucocutaneous tumors: Bowen's disease, non-melanoma skin cancers and genital carcinomas. This review discusses the characteristics of HPV, malignant and benign mucous and skin manifestations caused by HPV, besides the main methods of detection and typing of the virus. Keywords: DNA Viruses; Papillomavirus Infections; Warts Resumo: O papilomavírus humano (HPV) é um vírus DNA que apresenta tropismo por células epiteliais, causando infecções na pele e nas mucosas. A replicação do HPV ocorre no núcleo das células escamosas e o seu ciclo de vida é diretamente relacionado ao programa de diferenciação da célula hospedeira. Até o momento, foram completamente caracterizados cerca de 100 tipos diferentes de HPVs e há um grande número adicional de tipos ainda não sequenciados. Além de ser o responsável por lesões benignas de pele e mucosas, o HPV também está envolvido no desenvolvimento de diversos tumores cutaneomucosos: doença de Bowen, cânceres de pele não melanoma e carcinomas genitais. Esta revisão aborda as características do HPV, quadros cutâneos e mucosos benignos e malignos causados por ele e os principais métodos empregados em sua detecção e tipagem.

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Section: Alpha-papillomavirus (Supergroup A)mentioning

confidence: 99%

Section: Techniques For Detection Of Hpvmentioning

confidence: 99%

Section: Epidemiology Transmission and Pathogenesismentioning

confidence: 99%

Section: Common Wartsmentioning

confidence: 99%

See 2 more Smart Citations

Infecção pelo papilomavírus humano: etiopatogenia, biologia molecular e manifestações clínicas

Leto¹,

Júnior²,

Porro

et al. 2011

An. Bras. Dermatol.

113

View full text Add to dashboard Cite

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“…Zoster or girdle refers to occurrence of the disease in a segmental distribution. 1 Where as the majority of cases of chicken pox occur in the younger age group, old age is a major risk factor for herpes zoster. 2 It is usually accompanied by pain, the persistence of which is a problem especially in the elderly patients.…”

Section: Introductionmentioning

confidence: 99%