Visible-light-driven photoelectrochemical aptasensor based on reduced graphene oxide/Ti–Fe–O nanotube arrays for highly sensitive and selective determination of microcystin-LR

Research progress on photoelectrochemical sensors for contamination analysis in agricultural fields

“…In addition, the properties of the PEC sensors for MC-LR detection are presented in Table 4. 11,40,[165][166][167][168][169][170][171][172][173][174] As early as 2017, Liu et al developed a PEC aptasensor for MC-LR detection by using Z-scheme CdTe-Bi2S3 heterojunction as the photoelectrode materials. 165 When the MC-LR is captured by the aptamer on the surface of the photoelectrode, the photocurrent of the sensor decreases within the linear range of 1  10 -14 to 1  10 -10 mol/L, with a detection limit of 5  10 -15 mol/L (Fig.…”

Recent developments in the methods of quantitative analysis of microcystins

“…3D graphene-based biosensor MC-LR Abs 0.05 20 0.05 [110] Electrochemical biosensor Calf thymus DNA 0.004 0.512 0.0014 [111] Electrochemical immunoassay sensor Alkyne end-terminated Ab 0.01 200 0.004 [112] Electrochemical immunosensor Antigen of MC-LR 0.005 50 0.004 [113] Photoelectrochemical immunoassay sensor Ab of MC-LR 0.005 500 0.001 [114] Electrochemical immunosensor Ab of MC-LR 0.01 20 0.005 [115] Electrochemical impedance biosensor MC-LR aptamer 0.049 99.5 0.017 [116] Photoelectrochemical aptasensor MC-LR aptamer NA NA 1.691 × 10 −5 [ 117] Colorimetric sensor MC-LR aptamer 0.4 7462.5 0.368 [118] Fluorescence aptasensor MC-LR aptamer 0.01 50 0.002 [119] Fluorescence sensor MC-LR aptamer 0.398 1194 0.137 [119] Colorimetric sensor MC-LR aptamer NA NA 0.497 [120] Photoelectrochemical aptasensor Single-stranded DNA aptamer of MC-LR 0.01 5 5 × 10 −9 [ 122] Electrochemical aptasensor Thiolated MC-LR aptamers 5 × 10 −6 3 × 10 −2 2 × 10 −6 [ 123] Abbreviations: 3D, three-dimensional; Ab, antibody; MC, microcystin; NA, not available; LOD, limit of detection (the minimal amount of toxin whose presence or absence can be detected); LOQ, limit of quantification (upper and lower limits of the method are extremes of the linear range of the method); SPR, surface plasmon resonance; SWNT, single wall nanotubes.…”

“…Wang et al [121] have used an aptamer to form AuNP µg/L with a detection limit of 5 × 10 −9 µg/L. [122] Liu et al [123] have used a dual signal amplification strategy in an electrochemical aptasensor for the quantification of MC-LR. They nanosheets, which leads to a higher number of aptamers being immobilized on the surface.…”

Development and comparison of UPLC-ESI-MS and RP-HPLC-VWD methods for determining microcystin-LR

“…To date, several analytical techniques have been employed to determine MC-LR, such as enzyme-linked immunosorbent assays (ELISA), [20][21][22][23] protein phosphatase inhibition assays (PPIA), 24,25 chemical sensors and biosensors, [26][27][28][29][30][31][32] high performance liquid chromatography (HPLC) 33,34 and high performance liquid chromatography mass spectrometry (HPLC-MS). [35][36][37][38] ELISA is one of the most common and sensitive bioassay techniques for MC-LR detection.…”