Visible light-mediated three-component functionalization of olefins with sulfoxyimidoylsulfonium salt for the synthesis of β-amino alcohols and amino ethers

Abstract

A new strategy involving three-component functionalization of olefins with sulfoxyimidoylsulfonium salt and a nucleophilic reagent for the synthesis of β-amino alcohols and β-amino ethers by photoredox catalysis was developed.

Synthesis of N-Sulfinyl Sulfoximines from 5-(Sulfoximido)dibenzothiophenium Triflates and Sodium Sulfinates

“…At the outset of the study, 5-(sulfoximido)­dibenzothiophenium triflates 1a and sodium benzenesulfinate 2a were chosen as model substrates for the synthesis of N -sulfinyl sulfoximine 3a . Conducting the reaction at 60 °C in CH 3 CN, without the presence of any metals or additives, yielded desired product 3a with a 34% yield (Table , entry 1).…”