2024
DOI: 10.1002/cbic.202400922
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Visual and Quantitative Analysis of Dietary Fiber‐Microbiota Interactions via Metabolic Labeling In Vivo

Ningning Xu,
Huibin Lin,
Liyuan Lin
et al.

Abstract: Dietary fiber (DF)‐based interventions are crucial in establishing a health‐promoting gut microbiota. However, directly investigating DFs’ in vivo interactions with intestinal bacteria remains challenging due to the lack of suitable tools. Here, we develop an in vivo metabolic labeling‐based strategy, which enables not only imaging and identifying the bacteria that bind with specific DF in the intestines, but also quantifying DF’s impact on their metabolic status. Four DFs, including galactan, rhamnogalacturon… Show more

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