2024
DOI: 10.1002/em.22604
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Visualization strategies to aid interpretation of high‐dimensional genotoxicity data

Stephen D. Dertinger,
Erica Briggs,
Yusuf Hussien
et al.

Abstract: This article describes a range of high‐dimensional data visualization strategies that we have explored for their ability to complement machine learning algorithm predictions derived from MultiFlow® assay results. For this exercise, we focused on seven biomarker responses resulting from the exposure of TK6 cells to each of 126 diverse chemicals over a range of concentrations. Obviously, challenges associated with visualizing seven biomarker responses were further complicated whenever there was a desire to repre… Show more

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