Visualizing tumor angiogenesis and boundary with polygon-scanning multiscale photoacoustic microscopy

Xu, Zhiqiang; Pan, Yongjie; Chen, Ningbo; Zeng, Silue; Liu, Liangjian; Gao, Rongkang; Zhang, Jianhui; Fang, Chihua; Liu, Song; Liu, Chengbo

doi:10.1016/j.pacs.2022.100342

Cited by 20 publications

(17 citation statements)

References 40 publications

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“…• Limited to contrast from endogenous chromophores. [36,37] probe of endomicroscope was inserted through tracheotomy into the right lung. In both the mice, MSCs were detected which were injected via endotracheal (ET) and intravascular (IV) systems.…”

Section: Fpsmentioning

confidence: 99%

Exploring the future of regenerative medicine: Unveiling the potential of optical microscopy for structural and functional imaging of stem cells

Raju,

Nayak,

Acharya

et al. 2024

Journal of Biophotonics

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Regenerative medicine, which utilizes stem cells for tissue and organ repair, holds immense promise in healthcare. A comprehensive understanding of stem cell characteristics is crucial to unlock their potential. This study explores the pivotal role of optical microscopy in advancing regenerative medicine as a potent tool for stem cell research. Advanced optical microscopy techniques enable an in‐depth examination of stem cell behavior, morphology, and functionality. The review encompasses current optical microscopy, elucidating its capabilities and constraints in stem cell imaging, while also shedding light on emerging technologies for improved stem cell visualization. Optical microscopy, complemented by techniques like fluorescence and multiphoton imaging, enhances our comprehension of stem cell dynamics. The introduction of label‐free imaging facilitates noninvasive, real‐time stem cell monitoring without external dyes or markers. By pushing the boundaries of optical microscopy, researchers reveal the intricate cellular mechanisms underpinning regenerative processes, thereby advancing more effective therapeutic strategies. The current study not only outlines the future of regenerative medicine but also underscores the pivotal role of optical microscopy in both structural and functional stem cell imaging.

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Section: Fpsmentioning

confidence: 99%

Exploring the future of regenerative medicine: Unveiling the potential of optical microscopy for structural and functional imaging of stem cells

Raju,

Nayak,

Acharya

et al. 2024

Journal of Biophotonics

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“…The incident energy of the pulse laser absorbed by the targets is transformed into heat partially, and sound waves are instantaneously generated. [65][66][67] A high-resolution image of tissue can be provided by focusing light into biological tissue through optical objective lens and receiving photoacoustic signal in the same region by ultrasonic transducer. This method has been successfully applied to structure, function and molecular imaging in vivo.…”

Section: Photoacoustic Imagingmentioning

confidence: 99%

“…Photoacoustic (PA) imaging is a new kind of biomedical imaging technology utilizing thermoelastic effect. The incident energy of the pulse laser absorbed by the targets is transformed into heat partially, and sound waves are instantaneously generated [65–67] . A high‐resolution image of tissue can be provided by focusing light into biological tissue through optical objective lens and receiving photoacoustic signal in the same region by ultrasonic transducer.…”

Section: Biological Imagingmentioning

confidence: 99%

Progress of Mesoporous Silica Coated Gold Nanorods for Biological Imaging and Cancer Therapy

Ma,

Li,

Ying

et al. 2024

ChemMedChem

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For unique surface plasmon absorption and fluorescence characteristics, gold nanorods have been developed and widely employed in the biomedical field. However, limitations still exist due their low specific surface area, instability and tendency agglomerate in cytoplasm. Mesoporous silica materials have been broadly applied in field of catalysts, adsorbents, nanoreactors, and drug carriers due to its unique mesoporous structure, highly comparative surface area, good stability and biocompatibility. Therefore, coating gold nanorods with a dendritic mesopore channels can effectively prevent particle agglomeration, while increasing the specific surface area and drug loading efficiency. This review discusses the advancements of GNR@MSN in synthetic process, bio‐imaging technique and tumor therapy. Additionally, the further application of GNR@MSN in imaging‐guided treatment modalities is explored, while its promising superior application prospect is highlighted. Finally, the issues related to in vivo studies are critically examined for facilitating the transition of this promising nanoplatform into clinical trials.

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“…Also, a single wavelength in the NIR-I region can image the melanoma, however, surrounding blood vessels cannot be obtained. Therefore, the dual spectral band [23] , [24] or dual single wavelength laser [30] have been required to enhance the sensitivities by distinguishing between the melanoma and the blood vessels. Even though the NIR-II (1000–1700 nm) has a deeper penetration according to the reduced photon scattering compared with the visible ( e.g.…”

Section: Introductionmentioning

confidence: 99%

Efficient label-free in vivo photoacoustic imaging of melanoma cells using a condensed NIR-I spectral window

et al. 2023

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Visualizing tumor angiogenesis and boundary with polygon-scanning multiscale photoacoustic microscopy

Cited by 20 publications

References 40 publications

Exploring the future of regenerative medicine: Unveiling the potential of optical microscopy for structural and functional imaging of stem cells

Exploring the future of regenerative medicine: Unveiling the potential of optical microscopy for structural and functional imaging of stem cells

Progress of Mesoporous Silica Coated Gold Nanorods for Biological Imaging and Cancer Therapy

Efficient label-free in vivo photoacoustic imaging of melanoma cells using a condensed NIR-I spectral window

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