Visuo-vestibular contributions to anxiety and fear

Coelho, Carlos M.; Balaban, Carey D.

doi:10.1016/j.neubiorev.2014.10.023

Cited by 58 publications

(38 citation statements)

References 182 publications

(211 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The dizziness, ear pain, and subjective cognitive symptoms are aversive; as in the case of conditioned taste aversion in the presence of nausea and the symptoms may be attributed to irrelevant but novel conditions that merely coincide temporally with the proximate cause. Attribution and misattribution issues for balance disorders and nausea have been reviewed elsewhere . More recently, clinical evidence suggests that objective cognitive findings in patients with Otic capsule dehiscence syndrome are resolved by surgical repair .…”

Section: Discussionmentioning

confidence: 99%

Acute findings in an acquired neurosensory dysfunction

Hoffer

Levin

Snapp

et al. 2018

Laryngoscope Investig Oto

View full text Add to dashboard Cite

Background In the Autumn of 2016, diplomatic personnel residing in Havana began to present with symptoms of dizziness, ear pain, and tinnitus that emerged after perception of high frequency noise and/or a pressure sensation. Understanding the acute symptoms of this disorder is important for better defining the disorder and developing optimal diagnostic, preventive, and treatment algorithms. Objectives To define the presenting symptoms in a cohort of patients in the acute time period after perceiving a noise/pressure exposure in Havana. Design/Settings/Participants Review of 25 symptomatic individuals who reported a localized sensation of noise/pressure and 10 asymptomatic individuals (roommates of those affected) who did not experience the sound/pressure. Results Immediately after the exposure, the majority of individuals reported intense ear pain in one or both ears and experienced tinnitus. All of the individuals noticed unsteadiness and features of cognitive impairment. On presentation to our center, dizziness (92%) and cognitive complaints (56%) were the most common symptoms. Formal testing revealed that 100% of individuals had an otolithic abnormality and evidence of cognitive dysfunction. Conclusion and Relevance This study focuses on the acute presentation of a phenomenon in which symptoms emerge after perception of a localized noise/pressure and in which the acute symptomology includes the universal nature of vestibular injuries and select cognitive deficits. The findings presented in this acute group of patients begin to provide a better picture of the initial injury pattern seen after this exposure and may allow for more accurate diagnosis of this disorder in future cases. Level of Evidence Retrospective review

show abstract

Section: Discussionmentioning

confidence: 99%

Acute findings in an acquired neurosensory dysfunction

Hoffer

Levin

Snapp

et al. 2018

Laryngoscope Investig Oto

View full text Add to dashboard Cite

show abstract

“…However, other physiological changes may be associated with the pre-emetic stress response, including alterations in heart rate variability (Doweck et al, 1997; Kim et al, 2011; Kim et al, 2005) and a release of vasopressin from the posterior pituitary (Fisher et al, 1982; Robertson, 1976; Rowe et al, 1979; Sorensen et al, 1985). Along with these physiological responses are a number of perceptions with accompanying behavioral changes (Graybiel et al, 1968; Muth et al, 1996), including an awareness that stomach emptying is imminent, loss of appetite (Farmer et al, 2015; Heer et al, 2006; Hiura et al, 2012; Lackner, 2014; Sanger et al, 2013), anxiety and foreboding (Coelho et al, 2015; Fox et al, 1988; Lackner, 2014; Tarbell et al, 2014), as well as lethargy and disinterest in engaging in routine activities (Graybiel et al, 1976; Lackner, 2014; Lawson et al, 1998; Matsangas et al, 2014; Van Ombergen et al, 2015). The latter disengagement responses were first documented by Graybiel (Graybiel et al, 1976), and later described by others, who referred to them as the “sopite syndrome” (Graybiel et al, 1976; Lackner, 2014; Lawson et al, 1998; Matsangas et al, 2014; Van Ombergen et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

What is nausea? A historical analysis of changing views

Balaban

Yates

2017

Autonomic Neuroscience

Self Cite

View full text Add to dashboard Cite

The connotation of “nausea” has changed across several millennia. The medical term ‘nausea’ is derived from the classical Greek terms ναυτια and ναυσια, which designated the signs and symptoms of seasickness. In classical texts, nausea referred to a wide range of perceptions and actions, including lethargy and disengagement, headache (migraine), and anorexia, with an awareness that vomiting was imminent only when the condition was severe. However, some recent articles have limited the definition to the sensations that immediately precede emesis. Defining nausea is complicated by the fact that it has many triggers, and can build-up slowly or rapidly, such that the prodromal signs and symptoms can vary. In particular, disengagement responses referred to as the “sopite syndrome” are typically present only when emetic stimuli are moderately provocative, and do not quickly culminate in vomiting or disengagement from the triggering event. This review considers how the definition of “nausea” has evolved over time, and summarizes the physiological changes that occur prior to vomiting that may be indicative of nausea. Also described are differences in the perception of nausea, as well as the accompanying physiological responses, that occur with varying stimuli. This information is synthesized to provide an operational definition of nausea.

show abstract

“…The influence of anxiety on visuo-vestibular systems involved in balance control was initially described more than a century ago [Balaban and Jacob, 2001;Gowers, 1887], although only recent research has begun to examine the interactions across visual, vestibular, and anxiety systems [Balaban and Jacob, 2001;Carmona et al, 2009;Coelho and Balaban, 2015;Kapfhammer et al, 2014;Lopez, 2016;Mast et al, 2014].…”

Section: Introductionmentioning

confidence: 99%

Neuroticism modulates brain visuo-vestibular and anxiety systems during a virtual rollercoaster task

et al. 2016

View full text Add to dashboard Cite

Different lines of research suggest that anxiety-related personality traits may influence the visual and vestibular control of balance, although the brain mechanisms underlying this effect remain unclear. To our knowledge, this is the first functional magnetic resonance imaging (fMRI) study that investigates how individual differences in neuroticism and introversion, two key personality traits linked to anxiety, modulate brain regional responses and functional connectivity patterns during a fMRI task simulating self-motion. Twenty-four healthy individuals with variable levels of neuroticism and introversion underwent fMRI while performing a virtual reality rollercoaster task that included two main types of trials: (1) trials simulating downward or upward self-motion (vertical motion), and (2) trials simulating self-motion in horizontal planes (horizontal motion). Regional brain activity and functional connectivity patterns when comparing vertical versus horizontal motion trials were correlated with personality traits of the Five Factor Model (i.e., neuroticism, extraversion-introversion, openness, agreeableness, and conscientiousness). When comparing vertical to horizontal motion trials, we found a positive correlation between neuroticism scores and regional activity in the left parieto-insular vestibular cortex (PIVC). For the same contrast, increased functional connectivity between the left PIVC and right amygdala was also detected as a function of higher neuroticism scores. Together, these findings provide new evidence that individual differences in personality traits linked to anxiety are significantly associated with changes in the activity and functional connectivity patterns within visuo-vestibular and anxiety-related systems during simulated vertical self-motion. Hum Brain Mapp 38:715-726, 2017. © 2016 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.

show abstract

Visuo-vestibular contributions to anxiety and fear

Cited by 58 publications

References 182 publications

Acute findings in an acquired neurosensory dysfunction

Acute findings in an acquired neurosensory dysfunction

What is nausea? A historical analysis of changing views

Neuroticism modulates brain visuo-vestibular and anxiety systems during a virtual rollercoaster task

Contact Info

Product

Resources

About