Vitamin A deficiency during the perinatal period induces changes in vitamin A metabolism in the offspring. The regulation of intestinal vitamin A metabolism via ISX occurs only in male rats severely vitamin A-deficient

Abstract

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Bioaccumulated provitamin A in black soldier fly larvae is bioavailable and capable of improving vitamin A status of gerbils

“…Indeed, there was VA or proVA in the diet of all these groups and it is well established that serum retinol is very well regulated and only begins to decline when hepatic VA stores are nearly depleted (Borel et al, 2021b). Thus the fact that plasma retinol concentrations were not significantly lower in the C-group, as compared to the other groups, simply shows that this group was not deficient enough to affect hepatic retinol secretion and hence retinolemia (Borel et al, 2022;Borel et al, 2021b).…”

“…Then, 500 µL of the internal standard solution were added. The rest of the extraction procedure is identical to that described previously (Borel et al, 2022).…”

“…Thus, 50 μL of resolubilized kibbles samples, 25 μL of resolubilized hepatic samples and 180 µL of resolubilized blood samples were injected into the HPLC system. The HPLC system and method used (column, mobile phase, flow rate, detection method and spectral analysis software) were the same as previously described (Borel et al, 2022;Borel et al, 2021b)). Retinol, β-C and retinyl palmitate were identified by retention times and absorption spectra coincident with authentic standards.…”