Vitamin D and Allergy

Abstract

After the modern vitamin D hypothesis firstly suggested in 1999 for the allergy pandemic, numerous conditions have been thought to be associated with vitamin D deficiency such as allergy, autoimmunity and neoplasm. Consistently, previous observational studies have linked lower vitamin D status to increased markers of atopy and allergic diseases e.g. atopic dermatitis, anaphylaxis and food allergy. Vitamin D is a "hormone" having important immunomodulatory and immunoregulatory properties. In vitamin D deficient conditions, disrupted mucosal and skin complex integrity and intercurrent infections may act synergistically with allergenic exposure to amplify sensitization risk. There has been emerging data to show that vitamin D can enhance the anti-inflammatory effects of glucocorticoids and potentially be used as adjuvant therapy in steroid-resistant severe asthma. And recent in vivo data suggest that vitamin D supplementation reduce the severity of eczema and allergic rhinitis as well as urticaria symptoms. However, there is presently inadequate evidence to support daily vitamin D supplementation in the prevention and/or treatment of allergic diseases in infants, children and adolescents.

Controlling the electrical characteristics of Au/n‐Si structure with and without (biphenyl‐CoPc) and (OHSubs‐ZnPc) interfacial layers at room temperature

“…Besides these features, to understand electrical behavior of diodes and structures, they have been used as an interfacial layer. For instance, organic polymers such as PVA, [2,3] P2CIAn, [4,5] PEDOT, [6] polyindole [7] perylene [8] and phthalocyanine Pc, [9] and metal phthalocyanine (ZnPc) have recently attracted great attention in applications. Metal phthalocyanines have been very extensively used as dyes or pigments for many different applications since their discovery in 1930.…”