Vitiligo Associated with BCG-Methanol Extraction Residue in Malignant Melanoma

Cohen, Yair; Haim, S; Bartal, Alexandra; Robinson, Eve

doi:10.1159/000250737

Cited by 12 publications

(2 citation statements)

References 11 publications

(12 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The worldwide prevalence of vitiligo has been estimated as 0.5% 24 . The association between vitiligo and MM has been described by several investigators 1,2,8–10,25–46 . The relative rate of this association is still unknown; previous reports have given variable results ranging from 1.4% to 20% 29,30 .…”

Section: Discussionmentioning

confidence: 99%

Regressing cutaneous malignant melanoma and vitiligo‐like depigmentation

2004

View full text Add to dashboard Cite

Association of malignant melanoma (MM) with various clinical forms of skin depigmentation is well‐known. We report a case highlighting the importance of careful examination of patients with skin hypomelanoses, including vitiligo and halo nevi, in order to exclude the presence of MM. A 66‐year‐old woman presented with a 6‐month history of vitiligo‐like depigmentation of the face and halo nevi. Physical examination unexpectedly revealed also the presence of a regressing MM associated with a clinically evident lymphoadenopathy. Predominant dermoscopic features of the lesion were an irregular vascular pattern and regression structures, associated with peripheral areas of irregular pigmentation without pigment network. The literature concerning the association between leukoderma and MM is also reviewed.

show abstract

Section: Discussionmentioning

confidence: 99%

Regressing cutaneous malignant melanoma and vitiligo‐like depigmentation

2004

View full text Add to dashboard Cite

show abstract

“…Cohen et al [24] reported a pronounced vitiliginous reaction that developed at the sites of BCG methanol extraction residue injections given as an adjuvant immunotherapy to a patient with malignant melanoma. It may be a sign for an antimelanocytic effect and a further confi rmation for the autoimmune nature of vitiligo.…”

Section: Medications Used For the Treatment Of Melanomamentioning

confidence: 99%

Vitiligo – Exogenous Factors

Matz¹,

Tur²

2004

Exog Dermatol

View full text Add to dashboard Cite

Vitiligo is an acquired depigmentary disorder of the skin that results from the selective destruction of melanocytes. The etiology of vitiligo is poorly understood. There appears to be a genetic predisposition, but additional factors are probably involved. The purpose of this article is to outline the factors that might play a role in the development of vitiligo. These include trauma such as vaccination, radiotherapy, and sun exposure, malignancies and treatment of malignancies like lymphoma or melanoma, bone marrow transplantation, interferon, interleukin, and other drugs, psychological factors, endocrine disease and cytotoxic compounds that cause contact vitiligo. We hope future research will shed more light on the subject and identify the precipitating factors, since in the majority of vitiligo cases the contributing factors are as yet unidentified.

show abstract