A brief overview of the results of work in the field of “Devices, systems and technologies for medical purposes”, obtained with the direct participation of the authors of the article, is given. The results of the development and research in the field of modeling the effects of physical factors on the human body and digital processing of biomedical signals are presented. The principal aspects of the original systems of long-term monitoring of the human condition and control of the musculoskeletal system are presented.