Volatile oils: Potential agents for the treatment of respiratory infections

Pasdaran, Ardalan; Sheikhi, D.

doi:10.1016/b978-0-12-804543-5.00016-6

Cited by 7 publications

(5 citation statements)

References 95 publications

(122 reference statements)

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“…Nevertheless, investigations have focused on the assessment of the anti‐inflammatory potential of Monoterpene alcohols, including but not limited to linalool and linalyl acetate, as well as their corresponding esters. These compounds, recognized as prominent constituents among the volatile components of numerous aromatic plants, have exhibited considerable efficacy in combating inflammation, marking them as auspicious candidates within the realm of volatile bioactive agents [27] …”

Section: Resultsmentioning

confidence: 99%

“…These compounds, recognized as prominent constituents among the volatile components of numerous aromatic plants, have exhibited considerable efficacy in combating inflammation, marking them as auspicious candidates within the realm of volatile bioactive agents. [27] For example, aliphatic and aromatic aldehydes have been shown to have significant anti-inflammatory and antimicrobial properties 101. There is a good correlation between antiinflammatory activity and the terpenes and sesquiterpenes evaluated, which appear to be good 5-LOX inhibitors in vitro.…”

Section: Heat-induced Hemolysismentioning

confidence: 99%

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Analyzing the Bioactive Properties and Volatile Profiles Characteristics of Opuntia dillenii (Ker Gawl.) Haw: Exploring its Potential for Pharmacological Applications

El Hassania,

Mounime,

Elbouzidi

et al. 2024

Chemistry & Biodiversity

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In this investigation, the study focused on the chemical constitution and the antioxidative as well as anti‐inflammatory characteristics of oils and pulpy variants (Imatchan (IM), Harmocha (HA), and Aknari (AK)) sourced from O. dillenii. This inquiry encompassed both in vitro and in silico analyses. High‐performance liquid chromatography (HPLC) was employed to ascertain the phenolic constituents, while gas chromatography‐mass spectrometry (GC‐MS) methodologies. were applied to discern the volatile makeup. The anti‐inflammatory activity was examined using BSA and LOX. Molecular docking methods assessed the antioxidant and anti‐inflammatory properties. According to HPLC findings, the most abundant compounds detected in AKO and IMO cultivars were quercetin 3‐O‐β‐D‐glucoside followed by vanillic acid, ferulic acid and tyrolsol. The DPPH IC50 for AK, HA and IM were 38.41±1.54, 42.24±0.29 and 15.17±1.28 mg/mL, respectively. The AK, HA and IM O. dillenii oils were effective in their anti‐inflammatory activity. Molecular docking of O. dillenii oils phenolic compounds was conducted to determine the possible targeted proteins by the phenolic compounds in O. dillenii’s compounds. Overall, these fruits demonstrated the potential for new ingredients for culinary or pharmaceutical applications, providing value to these natural species that can flourish in arid conditions.

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Section: Resultsmentioning

confidence: 99%

Section: Heat-induced Hemolysismentioning

confidence: 99%

Analyzing the Bioactive Properties and Volatile Profiles Characteristics of Opuntia dillenii (Ker Gawl.) Haw: Exploring its Potential for Pharmacological Applications

El Hassania,

Mounime,

Elbouzidi

et al. 2024

Chemistry & Biodiversity

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“…The essential oil of C. sempervirens had a mild inhibitory outcome on SARS-CoV activity (700 ± 2.3 μg/ml) (Orhan and Tumen 2015;Loizzo et al 2008). Volatile oils are potential agents for treatment of SARS-CoV (Pasdaran et al 2016). An ethanolic extract of Thymus vulgaris Sm.…”

Section: Lebanonmentioning

confidence: 99%

Coronaviruses and Nature’s Pharmacy for the Relief of Coronavirus Disease 2019

Chinsembu

2020

Rev. Bras. Farmacogn.

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Current challenges to the treatment of coronavirus disease 2019 should open new prospects in the search for novel drugs from medicinal plants and other natural products. This paper provides details of natural agents that inhibit human coronavirus entry into cells, general replication, and specific chymotrypsin-like protease (3CL pro)-mediated replication. Medicinal plants, fungi, and marine organisms as remedies for human coronaviruses in China, Lebanon, Malaysia, Singapore, and South Africa are described. Common species include Alnus japonica (Thunb.

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“…Its extracts are traditionally used to relieve cough. It has anti-inflammatory, antiseptic, antibacterial, antioxidant, antimicrobial, and immunestimulating activity (146,147). Thyme extracts combined with other herbal plants have been tested to show significant relieving cough (148)(149)(150).…”

Section: Thymus Vulgarismentioning

confidence: 99%

Non-pharmacological remedies for post-viral acute cough

Ciprandi

Tosca

2021

Monaldi Arch Chest Dis

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The post-viral acute cough (PAC) is a widespread symptom, mainly in childhood and adolescence, and is usually associated with an acute upper respiratory infection, namely the common cold. The use of cough relievers is, therefore, impressive, as documented by the market data. There are many medical devices and dietary supplements for treating PAC, which contain non-pharmacological components. Ancient people used traditional herbs to treat PAC. Thus, a well-established tradition considers natural remedies as an effective and safe way to relieve PAC. The herbal agents include polyphenols, flavonoids, saponins, glucosides, and alkaloids. Also, the European Medicine Agency has recognized the value of plant extracts and other natural substances to treat PAC. Nevertheless, a few studies investigated the role of non-pharmacologic remedies for PAC. There is some evidence for honey, glycerol, Althea officinalis, Drosera rotundifolia, Grindelia, Hedera helix, Pelargonium sidoides, Sambucus nigra, Thymus vulgaris, hyaluronic acid, and saline solutions. However, further rigorous studies should confirm natural products' efficacy and safety to relieve PAC.

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Volatile oils: Potential agents for the treatment of respiratory infections

Cited by 7 publications

References 95 publications

Analyzing the Bioactive Properties and Volatile Profiles Characteristics of Opuntia dillenii (Ker Gawl.) Haw: Exploring its Potential for Pharmacological Applications

Analyzing the Bioactive Properties and Volatile Profiles Characteristics of Opuntia dillenii (Ker Gawl.) Haw: Exploring its Potential for Pharmacological Applications

Coronaviruses and Nature’s Pharmacy for the Relief of Coronavirus Disease 2019

Non-pharmacological remedies for post-viral acute cough

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