Handling Editor: H.-W. CaoThe Tabei Pb-Zn deposit is located adjacent to the well-known Axi low-sulphidation epithermal Au deposit in the Tulasu Basin, Chinese Western Tianshan. The homogenization temperatures and salinities of H 2 O-rich biphase inclusions in ore-stage sphalerite and calcite from Tabei range from 100 to 170 C and 0.4 to 6.2 wt% NaCleq, respectively. The δ 13 C V-PDB and δ 18 O V-SMOW values of calcite range from 0.9‰ to 1.5‰ and 5.6‰ to 6.7‰, respectively. The δ 18 O H2O and δD H2O values of hydrothermal fluids vary from À7.0‰ to À5.9‰ and À120.8‰ to À111.1‰, respectively. The in-situ δ 34 S V-CDT values of sulphides range from 7.5‰ to 8.0‰ (average 7.7‰). The in-situ Pb isotopic compositions of galena and ( 87 Sr/ 86 Sr) 0 ratios of sphalerite resemble those of Au-bearing pyrite and quartz of Axi deposit, respectively, as well as the ore-hosting volcanic rocks. These isotopic compositions indicate that the ore metals were derived from the ore-hosting volcanic rocks, with the oreforming fluids consisting predominantly of circulating meteoric water. The absence of coexisting two-phase vapour and liquid fluid inclusions and the presence of abundant banded coarse-grained quartz crystals with dog tooth and comb textures at Tabei, suggest that the sulphides precipitated slowly due to conductive cooling. The high sulphide abundance, sulphide assemblage (pyrite + Fe-poor sphalerite + galena + chalcopyrite), ore textures and isotopic compositions suggest that Tabei represents an intermediate-sulphidation epithermal deposit. The Axi-Tabei Au-Pb-Zn epithermal system constitutes a hybrid consisting of Au veins at shallow level and Pb-Zn veins at depth, suggesting that the base metals remain highly prospective beneath the identified Au orebodies at Axi.