Voltammetric Stripping Methods for Direct Determination of Disopyramide

Duran, Muharrem; Durmuș, Z.; Kılıç, Esma

doi:10.2174/157341212798995584

Cited by 3 publications

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“…4A and B that the potentials of both reduction processes on HMDE and potential of oxidation on GCE change with the scan rate. Changing of the potential with scan rate should be explained by quasireversible or irreversible mechanism [ 27 – 30 ]. As given in Fig.…”

Section: Resultsmentioning

confidence: 99%

Electrochemistry and determination of cefdinir by voltammetric and computational approaches

Taşdemir

2014

Journal of Food and Drug Analysis

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The oxidation and reduction behavior of cefdinir (CEF) was studied by experimental methods and computational calculations at B3LYP/6-31+G (d)//AM1. Voltammetric studies were carried out based on two irreversible reduction peaks at approximately -0.5 and -1.2 V on a hanging mercury drop electrode (HMDE) and on one irreversible oxidation peak at approximately 1.0 V on a glassy carbon electrode (GCE) versus Ag/AgCl, KCl (3.0M) in Britton-Robinson (BR) buffer at pH 4.2 and 5.0, respectively. Differential pulse adsorptive stripping voltammetric methods have been developed and validated for determination of CEF in different samples. The linear range was established as 0.25-40.0 μM for HMDE and 0.40-10.0 μM for GCE. Limit of quantification was calculated to be 0.20 and 0.26 μM for HMDE and GCE, respectively. These methods were successfully applied to assay the drug in tablets and human serum with good recoveries between 92.7% and 107.3% having relative standard deviation less than 10%.

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Section: Resultsmentioning

confidence: 99%

Electrochemistry and determination of cefdinir by voltammetric and computational approaches

Taşdemir

2014

Journal of Food and Drug Analysis

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Syntheses, characterization of and studies on the electrochemical behaviour of ferrocenyl dithiophosphonates and 4-methoxyphenyl dithiophosphonates

Sağlam

Erden

Tutsak

et al. 2016

Phosphorus, Sulfur, and Silicon and the Related Elements

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A cooperative computational and experimental investigation on electrochemical behavior of metoprolol and its voltammetric determination

et al. 2013

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The electrochemical behavior of metoprolol (MTP) was studied via experimental and computational approaches. Theoretical calculations were performed at the B3LYP/6-31+G(d)//AM1 level whereas experimental studies were carried out on a hanging mercury drop electrode (HMDE) and glassy carbon electrode (GCE). According to the computational results, both HOMO and LUMO of MTP were located at the phenyl ring. Hence, oxidation and reduction are expected to take place at the phenyl ring. Experimental studies on HMDE were based on reversible reduction at approximately –1.4 V and studies on GCE were based on irreversible oxidation at approximately 0.9 V versus Ag/AgCl (3 mol L−1 KCl) in Britton−Robinson buffer. Voltammetric methods with and without adsorptive stripping modes were developed. Proposed methods were successfully applied to tablet solutions and spiked human serum samples. Results are satisfactory with recovery values between 94.5% and 102.5% and a relative standard deviation lower than 6%.

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Voltammetric Stripping Methods for Direct Determination of Disopyramide

Cited by 3 publications

References 0 publications

Electrochemistry and determination of cefdinir by voltammetric and computational approaches

Electrochemistry and determination of cefdinir by voltammetric and computational approaches

Syntheses, characterization of and studies on the electrochemical behaviour of ferrocenyl dithiophosphonates and 4-methoxyphenyl dithiophosphonates

A cooperative computational and experimental investigation on electrochemical behavior of metoprolol and its voltammetric determination

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