Vorteile von Biomatrices bei der Chondrogenese von pluripotenten mesenchymalen Stammzellen

Abstract

The systematic investigation of biomatrices by chondrogenic progenitor cell culture systems may lead to important data for the evaluation of the chondrogenic potency biomatrices.

Joint Preserving Surgery for Osteonecrosis and Osteochondral Defects after Chemotherapy in Childhood

“…We used additional bone marrow aspirates combined with bone grafting in 3 cases to achieve a maximum of cell potential within the area to be regenerated. Different authors reported on the possible use of progenitor cells from different tissues like bone marrow and periosteum with or without scaffolds for bone and cartilage repair [1,2,7,13,17,28,34]. Although there are no clinical trials with a longer follow up, the high potential of these cellbased strategies is evident.…”

Tissue Engineering von Knorpelersatzgewebe – Mechanische Stimulation in der In-vitro-Kultivierung von humanen Chondrozyten

“…Das gleiche Problem verhinderte die Anwendung kommerziell erhältlichen Fibrinklebers als Trägermaterial (van Susante et al, 1999). Zum anderen werden MACT-Matrizes durch Fibrinkleber im Defektareal befestigt (Aicher et al, 2003) und Biomaterialien zwecks Verbesserung der Adhäsion mit Fibrin beschichtet (Jager et al, 2002 (Kock et al, 2011 (Li et al, 2005;Chung et al, 2006;Welsch et al, 2010).…”