Vortex fluidic induced mass transfer across immiscible phases

Abstract

Mixing immiscible liquids typically requires the use of auxiliary substances including phase transfer catalysts, microgels, surfactants, complex polymers and nano- particles and/or micromixers. Centrifugally separated immiscible liquids of different densities...

Exploiting angled thin film vortex microfluidics for expeditious syntheses of iminosugars

“…We note that the optimal tilt angle of 45° herein is common for a number of applications of the VFD, including those in materials processing and self-assembly. 30,31 This result and the variation in the optimal rotational speed for the different reactions is consistent with recent findings on the nature of the mechanical energy induced in the thin film of liquid in the VFD. 30,31 This is in the form of submicron high shear topological fluid flows in the 20 mm diameter quartz tube housed in the device and used herein, namely a spinning top (typhoon-like) arising from the Coriolis force from the hemispherical base of the tube, double helical flow associated with eddies from Faraday waves twisted by the side wall Coriolis force, and spicular flow as a combination of these when they are the same diameter.…”

“…30,31 This result and the variation in the optimal rotational speed for the different reactions is consistent with recent findings on the nature of the mechanical energy induced in the thin film of liquid in the VFD. 30,31 This is in the form of submicron high shear topological fluid flows in the 20 mm diameter quartz tube housed in the device and used herein, namely a spinning top (typhoon-like) arising from the Coriolis force from the hemispherical base of the tube, double helical flow associated with eddies from Faraday waves twisted by the side wall Coriolis force, and spicular flow as a combination of these when they are the same diameter. The variation in optimal rotational speed is also consistent with these studies, 30,31 in its dependence on the properties of the liquids, which are different for each reaction studied.…”

“…Errors were within AE3%. ‡ 1 optimal rotational speed is also consistent with these studies, 30,31 in its dependence on the properties of the liquids, which are different for each reaction studied. These topological uid ows are the internal uid ows in the VFD under conned mode of operation of the device, and also under continuous ow.…”

“…30,31 This is in the form of submicron high shear topological fluid flows in the 20 mm diameter quartz tube housed in the device and used herein, namely a spinning top (typhoon-like) arising from the Coriolis force from the hemispherical base of the tube, double helical flow associated with eddies from Faraday waves twisted by the side wall Coriolis force, and spicular flow as a combination of these when they are the same diameter. The variation in optimal rotational speed is also consistent with these studies, 30,31 in its dependence on the properties of the liquids, which are different for each reaction studied. These topological fluid flows are the internal fluid flows in the VFD under confined mode of operation of the device, and also under continuous flow.…”

Polymer and small molecule mechanochemistry: closer than ever

“…Looking into the future, one could expect that additional comparative studies between sonication and ball milling experiments will occur. At the same time, research into new modes to activate matter by force (e.g., twin-screw extrusion [71], resonant acoustic mixing [72], vortex fluidic mixing [73], laminar flow [74], etc.) will continue to unveil similarities and complementarities, rather than disparities, between the ways polymer and small molecule mechanochemical reactions occur.…”