2017
DOI: 10.1111/vox.12533
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Vox Sanguinis International Forum on platelet cryopreservation: Summary

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Cited by 19 publications
(19 citation statements)
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“…In recent years, there has been a relatively large resurgence of interest in CP as a promising blood product that is being used, tested, and validated in several countries and institutions. 15,22,[27][28][29][30][31] The US Army is engaged in a multi-million-dollar development effort for the production, manufacture, and approval (by the US Food and Drug Administration) of a CP product currently undergoing clinical trials. 32 At the Military University Hospital in Prague, Czech Republic, CPs are now used as a standard blood product.…”
Section: Discussionmentioning
confidence: 99%
“…In recent years, there has been a relatively large resurgence of interest in CP as a promising blood product that is being used, tested, and validated in several countries and institutions. 15,22,[27][28][29][30][31] The US Army is engaged in a multi-million-dollar development effort for the production, manufacture, and approval (by the US Food and Drug Administration) of a CP product currently undergoing clinical trials. 32 At the Military University Hospital in Prague, Czech Republic, CPs are now used as a standard blood product.…”
Section: Discussionmentioning
confidence: 99%
“…The publication of a no-wash protocol by Valeri et al in 2005 presented a gold standard cryopreservation protocol [9,10] and boosted the research field. The method hyperconcentrates the platelets by centrifugation after the addition of 6% (v/v) DMSO.…”
Section: Introductionmentioning
confidence: 99%
“…Reconstitution takes less than 30 minutes and requires minimal equipment and training. Dutch and Australian military experience in Afghanistan with 1143 cryopreserved PLT units transfused into 349 patients suggested they were both safe and effective, although no comparisons with liquid‐stored PLTs or whole blood were made. Extensive preclinical assessments have found that, compared to liquid‐stored PLTs, cryopreserved PLTs have increased procoagulant activity, with alterations in membrane receptors and higher microparticle concentrations .…”
mentioning
confidence: 99%