Wearable bioelectronic masks for wireless detection of respiratory infectious diseases by gaseous media

Wang, Bingfang; Yang, Deqi; Chang, Zhiqiang; Zhang, Ru; Dai, Jing; Fang, Yin

doi:10.1016/j.matt.2022.08.020

Cited by 25 publications

(16 citation statements)

References 53 publications

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“…While biosensors are most often used for biofluid analyses, they can also be engineered to detect airborne pathogens and biologically relevant gases. Gas sensors are an emerging field for flexible sensors.…”

Section: Sensing Performancementioning

confidence: 99%

“…For biosensors that do not rely on bioaffinity for sensing, careful engineering of catalytic nanomaterials can achieve desirable selectivity in the (electro)chemical recognition of some analytes. 127−129 While biosensors are most often used for biofluid analyses, they can also be engineered to detect airborne pathogens 130 and biologically relevant gases. Gas sensors are an emerging field for flexible sensors.…”

Section: Sensing Performancementioning

confidence: 99%

“…The form-factor challenges in compatible sensor-biology interfaces include mechanical robustness of nano-/microfabricated materials and devices, unaltered sensing performance, and reliable system integration between system components and with biological tissues. Innovations in device structural design, system layout and operation, and materials manufacture will bring about more effective solutions to these challenges and form factors that are presently rare (e.g., mask, 130,256,656,657 suture, 658 or bandage 563 ). Importantly, to design and to engineer materials and form factors that allow seamless integration with biological tissues, it is essential to understand in detail and in depth the anatomy, physiology, material properties, biological functions, etc.…”

Section: Sensor-biology Interfacementioning

confidence: 99%

“…Innovations in device structural design, system layout and operation, and materials manufacture will bring about more effective solutions to these challenges and form factors that are presently rare ( e.g. , mask, ,,, suture, or bandage). Importantly, to design and to engineer materials and form factors that allow seamless integration with biological tissues, it is essential to understand in detail and in depth the anatomy, physiology, material properties, biological functions, etc .…”

Section: Sensor-biology Interfacementioning

confidence: 99%

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Technology Roadmap for Flexible Sensors

et al. 2023

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Humans rely increasingly on sensors to address grand challenges and to improve quality of life in the era of digitalization and big data. For ubiquitous sensing, flexible sensors are developed to overcome the limitations of conventional rigid counterparts. Despite rapid advancement in bench-side research over the last decade, the market adoption of flexible sensors remains limited. To ease and to expedite their deployment, here, we identify bottlenecks hindering the maturation of flexible sensors and propose promising solutions. We first analyze challenges in achieving satisfactory sensing performance for real-world applications and then summarize issues in compatible sensor-biology interfaces, followed by brief discussions on powering and connecting sensor networks. Issues en route to commercialization and for sustainable growth of the sector are also analyzed, highlighting environmental concerns and emphasizing nontechnical issues such as business, regulatory, and ethical considerations. Additionally, we look at future intelligent flexible sensors. In proposing a comprehensive roadmap, we hope to steer research efforts towards common goals and to guide coordinated development strategies from disparate communities. Through such collaborative efforts, scientific breakthroughs can be made sooner and capitalized for the betterment of humanity.

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Section: Sensing Performancementioning

confidence: 99%

Section: Sensing Performancementioning

confidence: 99%

Section: Sensor-biology Interfacementioning

confidence: 99%

Section: Sensor-biology Interfacementioning

confidence: 99%

See 2 more Smart Citations

Technology Roadmap for Flexible Sensors

et al. 2023

Self Cite

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“…1). Such technology is only at an early stage of development and there are only a few examples of integrating biological and chemical sensors into face masks to detect pathogens or biomarkers associated with diseases [8][9][10] . In the future, optical, electrochemical and chemiresistive transducers could be integrated into In the future, chemical and biological sensing technologies could also be integrated into face masks to enable the detection of small and large molecules (for example, cortisol, hydrogen peroxide (H 2 O 2 ), nucleic acids and proteins), pathogens (for example, viruses, bacteria and fungi), gases and volatile organic compounds (VOCs; for example, ammonia (NH 3 ), carbon monoxide (CO) and acetone).…”

mentioning

confidence: 99%

Face masks as a platform for wearable sensors

et al. 2022

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Ultrasensitive Detection of SARS‐CoV‑2 by Flexible Metal Oxide Field‐Effect Transistors

Hou,

Wu,

et al. 2023

Adv Funct Materials

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The pandemic of coronavirus disease 2019 (COVID‐19) reflects the great significance of rapid and accurate detection of pathogens by new sensing technologies. Antibody based biosensors with high sensitivity comparable to golden standard polymerase chain reaction (PCR) and miniaturized device features allow the detection of pathogens in portable and flexible formats. Herein, flexible metal oxide electrolyte‐gated field‐effect transistors (EGFETs) are reported to serve as the biosensors for rapid and ultrasensitive severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) detection. The semiconducting layer of the EGFETs associates with hybrid material of PEI doped metal oxides that not only improves the transistor performance, but also regulates microstructure forming higher surface‐to‐volume ratio, which brings more antibodies immobilization, resulting in higher sensitive, and faster response for detecting SARS‐CoV‐2. Comprehensive studies of materials and interfacing engineering of the EGFETs not only build the strong foundation for the EGFET sensors to show excellent sensitivity with a limit of detection from 0.14 fg ml−1 for SARS‐CoV‐2 S1 proteins, and 0.09 copies µl−1 for SARS‐CoV‐2 viruses, but also offer good mechanical properties to enable thin, soft flexible sensing platforms. This work provides a new strategy from materials to devices as innovative schemes for virus/pathogens detection.

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Wearable bioelectronic masks for wireless detection of respiratory infectious diseases by gaseous media

Cited by 25 publications

References 53 publications

Technology Roadmap for Flexible Sensors

Technology Roadmap for Flexible Sensors

Face masks as a platform for wearable sensors

Ultrasensitive Detection of SARS‐CoV‑2 by Flexible Metal Oxide Field‐Effect Transistors

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