What about cerebral venous sinus thrombosis? A series of three autopsy cases

Tomassini, Luca; Paolini, Daniele; Petrasso, Pia Eugenia Ylenia; Manta, Anna Maria; Piersanti, Valeria; Straccamore, Marco; Ciallella, Costantino

doi:10.1016/j.legalmed.2022.102052

Cited by 2 publications

(3 citation statements)

References 32 publications

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“…In this case, the patient presented with the sole sign of unilateral CN VI palsy without any other symptoms, which was reported once, according to the literature search, where the thrombosis is only localized to the transverse sinus [ 11 ]. CVST of idiopathic etiology with isolated abducens nerve palsy as the sole presentation is rare.…”

Section: Discussionmentioning

confidence: 99%

“…Thrombosis of the cerebral veins and sinuses is a rare but significant cause of stroke, accounting for 0.5-1.0% of stroke admissions, with an estimated incidence of three to four per million people annually [10]. It is an underdiagnosed condition because of the wide range of signs and symptoms and similarities with many neurological conditions [11]. Towbin (1973) reported a study based on 189 consecutive autopsied cases in three years.…”

Section: Cavernous Venous Sinus Thrombosismentioning

confidence: 99%

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Unilateral Abducens Nerve Palsy as the Lone Sign of Cerebral Venous Sinus Thrombosis: A Case Report and Literature Review

Ong¹,

Yong²,

Khialdin³

et al. 2023

Cureus

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Cerebral venous thrombosis (CVT) is a rare condition characterized by the obstruction of cerebral venous sinuses or cortical veins, leading to stroke-like symptoms. This case report presents a case of a 74-year-old male with isolated unilateral abducens nerve palsy as the sole sign of CVT, without accompanying symptoms or focal deficits. Neuroimaging, including CT and magnetic resonance venography, confirmed the diagnosis of CVT with a thrombus in the right transverse sinus. The patient was co-managed with the medical team and initiated on anticoagulation therapy. Follow-up showed resolution of diplopia and improvement in extraocular muscle movements. Unilateral abducens nerve palsy in CVT is rare, with most cases presenting as bilateral palsy. The case report emphasizes the importance of considering CVT in the differential diagnosis of isolated abducens nerve palsy and highlights the role of neuroimaging in early detection. Timely diagnosis and appropriate management are crucial for favorable outcomes in CVT cases. Further research is needed to enhance understanding of the pathophysiology, prognosis, and optimal management of this uncommon presentation.

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Section: Discussionmentioning

confidence: 99%

Section: Cavernous Venous Sinus Thrombosismentioning

confidence: 99%

Unilateral Abducens Nerve Palsy as the Lone Sign of Cerebral Venous Sinus Thrombosis: A Case Report and Literature Review

Ong¹,

Yong²,

Khialdin³

et al. 2023

Cureus

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“…Cerebral venous sinus thrombosis (CVST) is an uncommon condition characterized by the formation of blood clots in the cerebral venous system [1]. Its variable clinical presentation can result in a wide range of neurological symptoms and diagnostic challenges.…”

Section: Introductionmentioning

confidence: 99%

Lower cranial neuropathy as a presentation of cerebral venous sinus thrombosis secondary to antiphospholipid syndrome: A case report

Mohammed Rafi,

Khan,

Alomar

et al. 2024

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Cerebral venous sinus thrombosis (CVST) is a rare cause of stroke especially among young adults. The clinical presentation of CVST is diverse, which makes the diagnosis to be challenging. Lower cranial neuropathy is a rare presentation of CVST, with few cases in literature. We are describing a case of 39-year-old male patient, presented with left occipital neuralgia, with left lower cranial neuropathies due to left transverse and sigmoid sinus thrombosis; secondary to antiphospholipid syndrome, with good response to anticoagulation.

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What about cerebral venous sinus thrombosis? A series of three autopsy cases

Cited by 2 publications

References 32 publications

Unilateral Abducens Nerve Palsy as the Lone Sign of Cerebral Venous Sinus Thrombosis: A Case Report and Literature Review

Unilateral Abducens Nerve Palsy as the Lone Sign of Cerebral Venous Sinus Thrombosis: A Case Report and Literature Review

Lower cranial neuropathy as a presentation of cerebral venous sinus thrombosis secondary to antiphospholipid syndrome: A case report

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