What Factors Affect Intracytoplasmic Sperm Injection Outcomes?

Lewis, Sacha; Klonoff-Cohen, Hillary

doi:10.1097/01.ogx.0000153330.63877.9c

Cited by 12 publications

(8 citation statements)

References 76 publications

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“…Current studies suggest that the use of fresh or frozen-thawed sperm does not appear to affect ICSI outcomes [111]. Testicular tissue and epididymal sperm can be cryopreserved successfully without markedly reducing subsequent fertilization and implantation rates and repeated testicular biopsy can be avoided without the risk of any decrease in the outcome [112].…”

Section: Sperm Originmentioning

confidence: 99%

Intracytoplasmic Sperm Injection – Factors Affecting Fertilization

Javed¹,

Michael²

2012

Enhancing Success of Assisted Reproduction

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Section: Sperm Originmentioning

confidence: 99%

Intracytoplasmic Sperm Injection – Factors Affecting Fertilization

Javed¹,

Michael²

2012

Enhancing Success of Assisted Reproduction

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“…Several studies have tried to identify the underlying causes of the limited success rate of ICSI, for example advanced maternal age or sperm origin (testicular, epididymal or ejaculated). However, no good explanation has been found yet [ 6 – 8 ].…”

Section: Introductionmentioning

confidence: 99%

Does the genetic and familial background of males undertaking ICSI affect the outcome?

Maiburg

Alizadeh

Kastrop

et al. 2009

J Assist Reprod Genet

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Purpose To investigate whether the success rate of ICSI is (1) related to the etiology of infertility or (2) adversely affected by a family history of potential genetic disorders. Methods All men with an ICSI indication in our hospital between 1994 and 2005 were included in our cohort study. Data on the ICSI process, etiology of infertility, and family history were collected. ICSI success rates of infertility subgroups and a subgroup with a positive family history were compared to a group with unknown etiology and a negative family history. Results There was no significant difference in clinical pregnancy or delivery rates between the subgroups. Couples achieving a pregnancy underwent significantly more ICSI cycles compared to couples not achieving a pregnancy. ConclusionOur results suggest that the success rate of ICSI treatment is not related to the cause of infertility or a family history positive for potential genetic disorders.

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“…The factors that affect its outcome have been recently reviewed. 14 Almost all clinics have to provide the three abovedescribed alternatives, in addition to the "usual" IVf-ET. On the average it costs $6,000-to $8,000 per cycle.…”

Section: Embryo Transfermentioning

confidence: 99%

“…Only one sperm penetrates the oocyte, and fertilization occurs. The resulting zygote continues its journey down the fallopian tube for 2-3 days and, during its transit, continues to divide into approximately [8][9][10][11][12][13][14][15][16] cells. The pre-embryo then enters the uterus in the blastocyst stage and after 2-3 days it implants itself in the uterus and grows over the next 39 weeks.…”

Section: Normal (Coital) Reproductionmentioning

confidence: 99%

Islamic Shari'ah Rulings on New Reproductive Choices

Fadel

2005

J Islam Med Assoc

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Infertility is a serious hardship. There have been several advancements in its management. A major breakthrough in 1978 was the successful achievement of pregnancy and the birth of a girl as a result of In Vitro Fertilization (IVF). That success led to several technological innovations that heralded a new era of "Non Coital Reproduction". These methods are collectively known as "Assisted Reproductive Technologies (ARTs)." These are now available to women all across the USA and in many other countries. Thousands of couples are achieving pregnancies through the use of ARTs every year. Most of these couples would otherwise never have achieved pregnancies.Although this is a welcome addition to the medical armentarium, there are several unresolved ethical, societal and religious concerns about their applications, especially in regards to the more recent applications of IVF.A brief account of "normal" procreation and the basic principles of ARTs are given. Then the sharfa (Islamic law) principles that guide us in deciding the acceptability of these technologies will be discussed. Then the rulings that have been agreed upon by Islamic scholars will be given. Briefly stated, Islam not only allows but also encourages married couples to seek treatment of infertility, including the use of ARTs. However, certain limits cannot be crossed. The Islamic principles that identify these limits are 1) a valid marriage contract; 2) preservation of lineage including adopted offspring; 3) surrogacy is prohibited and the "birth mother" is the mother; and 4) gametes are not to be donated.

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What Factors Affect Intracytoplasmic Sperm Injection Outcomes?

Abstract: After completion of this article, the reader should be able to explain the procedure, intracytoplasmic sperm injection (ICSI), to outline the data surrounding chromosomal and developmental outcomes after ICSI, and to list and explain the potential factors that influence ICSI.

Cited by 12 publications

References 76 publications

Intracytoplasmic Sperm Injection – Factors Affecting Fertilization

Intracytoplasmic Sperm Injection – Factors Affecting Fertilization

Does the genetic and familial background of males undertaking ICSI affect the outcome?

Islamic Shari'ah Rulings on New Reproductive Choices

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