What have we learnt from the inhibition of IL-6 in RA and what are the clinical opportunities for patient outcomes?
Peter C. Taylor,
Eugen Feist,
Janet E. Pope
et al.
Abstract:Rheumatoid arthritis (RA) is an autoimmune disease characterised by persistent inflammation of the synovial joints as well as other tissues and organs. Left untreated, it can lead to joint damage, disability and even increased mortality. The disease is driven by inflammatory cytokines that contribute to the chronic inflammation seen in RA. Interleukin-6 (IL-6) is a key pathological cytokine and a target for treatments aiming to alleviate local and systemic inflammation. Despite advances in understanding RA and… Show more
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