What holds back colon capsule endoscopy from being the main diagnostic test for the large bowel in cancer screening?

Performance of a Deep Learning System for Automatic Diagnosis of Protruding Lesions in Colon Capsule Endoscopy

“…Moreover, CCE may not only be seen as an alternative to conventional colonoscopy but rather as a complementary solution in programmed screening settings. Indeed, CCE may help to shorten waiting lists, decrease hospital appointments and make screening available to remote areas [ 27 ]. In this setting, the cost-effectiveness of CCE appears to be greater when the prevalence of colorectal cancer is lower and the uptake rate is superior to that of conventional colonoscopy [ 28 ].…”

The effectiveness of a very low-volume compared to high-volume laxative in colon capsule endoscopy

“…Furthermore, the doubleheaded camera capsules are being applied for panenteric investigations, with promising results [11][12][13][14][15][16]. To achieve viable wider CCE adoption, challenges regarding completion rates (CR) and adequate cleanliness rates (ACR) must be handled [17,18]. CR and ACR should be improved to meet the standards for optical colonoscopy (OC) from the European Society of GI Endoscopy (ESGE).…”

Current status of colon capsule endoscopy in clinical practice

“…One major issue that prevents a more widespread use is the high number of patients that need a colonoscopy after the CCE, either because the CCE was of insufficient quality or because positive findings demand a therapeutic procedure 5 . Studies of patient preference and the economy of CCE delivery indicate that the reinvestigation rate should be lower than approximately 30% to obtain a patient selection over a colonoscopy 6 .…”