Environmental and socioeconomic drivers would alter landscapes, bringing various effects with different directions and magnitudes. Demonstrating these driving effects is key to relieving the conflicts between territorial vegetation restoration and regional economic growth. However, the relationship between ecological protection and economic development due to landscape dynamics has not been systematically demonstrated as environment is difficult to quantify by the monetary value. In this article, we explored the changes in gross ecosystem product (GEP) in the Three Gorges (TG) reservoir area and constructed a conceptual framework to explicate its driving mechanism. Our results suggested that topographic, soil, and climatic factors positively impact on GEP through their important effects on vegetation structure, distribution, and succession. Additionally, reforestation policies promote the conversion of farmland and grassland to forestland in the TG reservoir region, which was the main contributor to enhancing GEP. Conversely, socioeconomic factors negatively impact GEP, of which effects were mainly manifested by changes in the proportion of ecological land. Therefore, it is essential to maintain a suitable land use proportion in this region to optimize GEP, and we proposed a landscape restoration program to enhance four ecosystem productions. This article provides a reference for land resource allocation for environmental protection and sustainable development in ecologically fragile areas.