What is the likelihood that Thoroughbred foals treated for septic arthritis will race?

Smith, L. J.; Marr, Celia M.; Payne, Richard J.; Stoneham, Sarah J.; Reid, S.

doi:10.2746/0425164044868396

Cited by 70 publications

(109 citation statements)

References 9 publications

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“…48 However, recent studies, 31,37,[39][40][41]49,50 including ours, have failed to find such an association. In the present study, median (range) duration of clinical signs before admission to the hospital in group 1 was 4 days (0 to 60 days), which is longer than in other studies, 38,40 which have reported higher survival rates. Wereszka et al 15 found that duration of clinical signs prior to admission to the hospital < 1 day was associated with higher survival rates than clinical signs > 10 days.…”

Section: Discussioncontrasting

confidence: 48%

“…Foals and adults were evaluated together, but age was not a significant factor in the multivariate analysis. Our study population was purely referral, compared with other studies 38,40 that also included primary cases. In fact, 74% of the patients in this study had received treatment by referring veterinarians before admission to the hospital, and 17% of cases had received intrasynovial antimicrobials.…”

Section: Discussionmentioning

confidence: 99%

“…It was our purpose to be as specific as possible when defining sepsis in a synovial structure and to evaluate septic synovitis and nonseptic contaminated intrasynovial lacerations separately. Previous studies 15,24,[33][34][35][36][37][38][39] evaluating septic synovitis in horses have found survival rates of 62% to 92% in adults and 42% to 85% in foals. In our study, 72% of horses with septic synovitis were discharged from the hospital, and 53.43% of the horses with follow-up information available were alive at long-term follow-up.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, a higher proportion of cases refractory to primary treatment might have been included, compared with other studies. 38 Positive results of bacterial cultures have been associated with a lower survival rate. 41 In group 1, 59.26% of bacterial cultures were positive, which lies in the upper portion of the range of reported culture success rates (22% to 74%) 24,[42][43][44] and might indicate high severity of disease.…”

Section: Discussionmentioning

confidence: 99%

“…This has been reported and is especially relevant in young foals. 4,15,34,38,51 In this study, only 7 foals with multiple joints affected were included, and of those, only 3 survived. Concurrent osteomyelitis has also been reported to negatively influence prognosis 4,36,39,52 ; however, that was not observed in the present study.…”

Section: Discussionmentioning

confidence: 99%

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Clinical use of antimicrobial regional limb perfusion in horses: 174 cases (1999–2009)

Rubio‐Martínez

Elmas²,

Black³

et al. 2012

javma

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Objective—To describe the clinical use of regional limb perfusion with antimicrobials (A-RLP), complications, and outcome in a large series of patients. Design—Retrospective case series. Animals—174 horses. Procedures—Medical records of horses treated with A-RLP between 1999 and 2009 were reviewed. Signalment, primary complaint, horse use, etiology, duration of clinical signs, previous treatment, structures involved, concurrent conditions, A-RLP characteristics, additional treatments, complications, and outcome were recorded. At long-term follow-up, 2 outcomes were investigated: survival rate and return to previous use at the same or higher level. Univariate and multivariate logistic regression analyses were conducted. Results—Group 1 (96 horses) included septic synovitis. Group 2 (50 horses) included extrasynovial lacerations (23 horses) and fresh, minimally contaminated intrasynovial lacerations without evidence of established synovial infection (27 horses). Group 3 (28 horses) included miscellaneous other conditions. Only minor complications were reported in 12.26% of horses that received IV (n = 155) and 33% of horses that received intraosseous (27) A-RLP. Horses with septic synovitis had a lower survival rate (53.43%) than did horses with lacerations (91.89%). Within group 2, no significant differences in short- or long-term outcomes were found between horses with extrasynovial and fresh, minimally contaminated intrasynovial lacerations. For the horses returning to previous use, 80% of horses with septic synovitis and 72.72% of horses with lacerations were performing at the same or higher level at the time of follow-up. Conclusions and Clinical Relevance—The results of the present study indicated that A-RLP is a safe technique with minimal adverse effects. The IV route presented fewer complications than intraosseous injection. Horses with infection of synovial structures had a lower survival rate than did those with acute, minimally contaminated intrasynovial lacerations. The latter had a similar prognosis for horses with extrasynovial lacerations treated with A-RLP.

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