What Role do Circadian Rhythms Play in Learning and Memory?

Mou, Xiang

doi:10.4172/2155-9562.1000367

Cited by 3 publications

(2 citation statements)

References 73 publications

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“…Circadian rhythms are fundamental biological concepts that are conserved in multiple organisms. A network of circadian neurons in the fruit fly Drosophila melanogaster drives daily rest and activity rhythms [ 85 ]. In the central nervous system and on the periphery, including in the hippocampus, circadian rhythmicity in gene expression and physiological processes was observed.…”

Section: Discussionmentioning

confidence: 99%

Differential gene expression analysis following olfactory learning in honeybee (Apis mellifera L.)

et al. 2022

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Insects change their stimulus-response through the perception of associating these stimuli with important survival events such as rewards, threats, and mates. Insects develop strong associations and relate them to their experiences through several behavioral procedures. Among the insects, Apis species, Apis mellifera ligustica are known for their outstanding ability to learn with tremendous economic importance. Apis mellifera ligustica has a strong cognitive ability and promising model species for investigating the neurobiological basis of remarkable olfactory learning abilities. Here we evaluated the olfactory learning ability of A. mellifera by using the proboscis extension reflex (PER) protocol. The brains of the learner and failed-learner bees were examined for comparative transcriptome analysis by RNA-Seq to explain the difference in the learning capacity. In this study, we used an appetitive olfactory learning paradigm in the same age of A. mellifera bees to examine the differential gene expression in the brain of the learner and failed-learner. Bees that respond in 2nd and 3rd trials or only responded to 3rd trials were defined as learned bees, failed-learner individuals were those bees that did not respond in all learning trials The results indicate that the learning ability of learner bees was significantly higher than failed-learner bees for 12 days. We obtained approximately 46.7 and 46.4 million clean reads from the learner bees failed-learner bees, respectively. Gene expression profile between learners’ bees and failed-learners bees identified 74 differentially expressed genes, 57 genes up-regulated in the brains of learners and 17 genes were down-regulated in the brains of the bees that fail to learn. The qRT-PCR validated the differently expressed genes. Transcriptome analyses revealed that specific genes in learner and failed-learner bees either down-regulated or up-regulated play a crucial role in brain development and learning behavior. Our finding suggests that down-regulated genes of the brain involved in the integumentary system, storage proteins, brain development, sensory processing, and neurodegenerative disorder may result in reduced olfactory discrimination and olfactory sensitivity in failed-learner bees. This study aims to contribute to a better understanding of the olfactory learning behavior and gene expression information, which opens the door for understanding of the molecular mechanism of olfactory learning behavior in honeybees.

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Section: Discussionmentioning

confidence: 99%

Differential gene expression analysis following olfactory learning in honeybee (Apis mellifera L.)

et al. 2022

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“…To achieve the best results in personification it is wise to use not only user explicit characteristics but also nonexplicit ones, such as circadian rhythms for example. There are detailed studies of the effects of circadian rhythm on learning [2,3].…”

Section: Introductionmentioning

confidence: 99%

The Personification of the User’s Interface: Classification vs. Clusterization of Users of Online Courses

Matrosova

Shtennikov

2019

ETR

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Researchers compared the classification and the clusterization of users of online course for the personification of the users’ information system interface. When interacting with control and information systems, users may manifest individual features, including implicit characteristics that may affect one’s results within the system. At the same time due to information system building peculiarities one of the most comprehensive statistics can be collected via e-learning systems. When using a course, the user leaves a wide trail of activity that may contain different information depending on the learning environment structure. Online blended learning courses draw the researcher’s attention to the impact of digital teaching models on students as well as its ability to adjust distant learning courses to individual students’ needs and differences. Information personalization is a highly relevant content presentation at the most individual level. Therefore, the task of personalization is to show users information that meets their needs and interests. Personalization gives the opportunity to focus on points that have real value for users.

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Chronic light deprivation induces different effects on spatial and fear memory and hippocampal BDNF/TRKB expression during light and dark phases of rat diurnal rhythm

Asadian

Parsaie

Vafaei

et al. 2022

Behavioural Brain Research

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What Role do Circadian Rhythms Play in Learning and Memory?

Cited by 3 publications

References 73 publications

Differential gene expression analysis following olfactory learning in honeybee (Apis mellifera L.)

Differential gene expression analysis following olfactory learning in honeybee (Apis mellifera L.)

The Personification of the User’s Interface: Classification vs. Clusterization of Users of Online Courses

Chronic light deprivation induces different effects on spatial and fear memory and hippocampal BDNF/TRKB expression during light and dark phases of rat diurnal rhythm

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