This study comprises a systematic literature review of 68 articles published between 2010 and 2024, identifying and coherently grouping the wine tourism sector’s adoption of technological innovation practices. The articles were analyzed using a framework developed from the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The selection criteria included peer-reviewed, full-length articles in English emphasizing technological innovations in the wine tourism sector. The results highlight several key trends in technological innovation applied to wine tourism. The innovations were categorized into five areas: digital marketing and promotion, sustainability and innovation, immersive technologies (AR/VR), e-commerce and distribution models, and smart technologies for winery management. The review reveals a growing interest in digital marketing and immersive technologies in promoting wine tourism through digital platforms and creating engaging tourist experiences through virtual and augmented reality. The review focuses only on peer-reviewed studies published in English, which may limit its global scope. Books and non-peer-reviewed articles may have introduced further developments in technological innovation that are not captured in this review. This study is a post-COVID-19 review of technological innovation in wine tourism. The findings provide significant implications for researchers and policymakers, suggesting future research areas and offering insights on how public funds can support wine tourism’s digital transformation and sustainability