2023
DOI: 10.26434/chemrxiv-2023-gr155
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Which boronic acids are used most frequently for synthesis of bioactive molecules ?

Peter Ertl,
Eva Altmann,
Sophie Racine
et al.

Abstract: Boronic acids are essential building blocks used for the synthesis of bioactive molecules, the generation of chemical libraries and the exploration of structure-activity relationships. As a result, more than ten thousand boronic acids are commercially available. Medicinal chemists are therefore facing a challenge; which of them should they select to maximize information obtained by the synthesis of new target molecules. The present article aims to help them to make the right choices. The boronic acids used fre… Show more

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