White adipose tissue remodeling in Little Brown Myotis (Myotis lucifugus) with white-nose syndrome
Evan L. Pannkuk,
Marianne S. Moore,
Shivani Bansal
et al.
Abstract:White-nose syndrome (WNS) is a fungal wildlife disease of bats that has caused precipitous declines in certain Nearctic bat species. A key driver of mortality is premature exhaustion of fat reserves, primarily white adipose tissue (WAT), that bats rely on to meet their metabolic needs during winter. However, the pathophysiological and metabolic effects of WNS have remained ill-defined. To elucidate metabolic mechanisms associated with WNS mortality, we infected a WNS susceptible species, the Little Brown Myoti… Show more
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