“…DTI facilitates the in vivo study of brain white matter (WM) microstructure (Mori et al, 2008), and typical DTI measures include fractional anisotropy (FA), mean (MD), axial (AD) and radial diffusivity (RD). Alterations in these metrics are reported in 22q11DS (Barnea-Goraly et al, 2003; da Silva Alves et al, 2011; Deng et al, 2015; Kates et al, 2015; Kikinis et al, 2012; Martin et al, 2014; Ottet et al, 2013; Padula et al, 2015; Radoeva et al, 2012; Scariati et al, 2016; Sundram et al, 2010; Villalon-Reina et al, 2013), and some of the patterns observed are similar to deficits in SZ (Kyriakopoulos et al, 2008; Roalf et al, 2015; Thomason and Thompson, 2011), adolescents with psychosis (Davenport et al, 2010; White et al, 2007) and youth at risk for developing psychosis (Epstein et al, 2013; Lee et al, 2013). In contrast to structural gray matter findings, DTI results in 22q11DS are more inconsistent.…”