White Paper on P4 Concepts for Pediatric Imaging

Abstract

Over the past decade, innovations in the field of pediatric imaging have been largely based on single center and retrospective studies, which provided limited advances for the benefit of pediatric patients. In order to identify opportunities for potential quantum leap progress to the field of Pediatric Imaging, the American College of Radiology - Pediatric Imaging Research (ACR - PIR) Committee has identified high impact research directions related to the P4 Concept of Predictive, Preventive, Personalized, and Participatory Diagnosis and Intervention. Input from 237 members of the Society for Pediatric Radiology was clustered towards ten priority areas, which will be discussed in this article. Needs of each priority area have been analyzed in detail by dedicated ACR-PIR experts in these topics. By facilitating work on these priority areas, we hope to revolutionize the care of children by shifting our efforts from unilateral reaction to clinical symptoms to interactive maintenance of child health.

Use of modern three‐dimensional imaging models to guide surgical planning for local control of pediatric extracranial solid tumors

“…As such, there has been a recent interest in the utility of three‐dimensional (3D) imaging for this population. This has been further amplified by White Paper publications and establishment of guidelines by both the American College of Radiology and the Radiological Society of North America 7,8 . While magnetic resonance imaging (MRI) and computed tomography (CT) have been the foundation of preoperative oncologic imaging, 4 incorporating 3D modeling and printing for enhanced visualization appears beneficial 9 …”

“…This has been further amplified by White Paper publications and establishment of guidelines by both the American College of Radiology and the Radiological Society of North America. 7,8 While magnetic resonance imaging (MRI) and computed tomography (CT) have been the foundation of preoperative oncologic imaging, 4 incorporating 3D modeling and printing for enhanced visualization appears beneficial. 9 Specifically, within pediatric oncology, previous work has suggested that 3D printing may be useful for complex tumor resections, 10,11 though these techniques have yet to be published within the United…”

European Society of Paediatric Radiology 2019 strategic research agenda: improving imaging for tomorrow’s children

“…Several of these initiatives (particularly dose reduction and optimisation, data registries and improving image analysis) are shared with other paediatric imaging representatives, such as the Paediatric Imaging Research Committee of the American College of Radiology (White paper [41]) and we look forward to joint initiatives.…”

Vom Röntgen zum PET/MRT, und dann? – Zukunftsweisende Bildgebung in der Kinderradiologie

“…Zukunftsweisende Konzepte zielen darauf ab, die Akzeptanz der MRT-Untersuchung zu verbessern und die Methodik für ein erweitertes Indikationsspektrum mit konkreten, klinisch relevanten Endpunkten zu etablieren [8]. Mithilfe einer Kombination aus pädagogisch-spielerischen Ansätzen und neuen MRT-Techniken lässt sich das Risikoprofil der MRT verbessern und hierdurch die Notwendigkeit einer Sedierung und die Verwendung von Gadolinium-haltigen Kontrastmitteln minimieren.…”

“…Diese Anwendung könnte z. B. für die nichtinvasive Überwachung der Oxygenierung des Gehirns und der Viszeral-Organe bei Frühgeborenen eingesetzt werden[8].Positronen-Emissionstomografie (PET) und PET/CT PET und PET/CT sind seit vielen Jahren für die molekulare Bildgebung von pädiatrischen Tumoren etabliert [55]. Zu den Vorteilen gehören die hohe Empfindlichkeit (Erkennung von Pikomolar-Konzentrationen) und ein hoher Tumor-zu-Hintergrund-Kontrast.…”