Whole-Body Computed Tomography Imaging in Cancer Staging

Collivignarelli, Francesco; Signore, Francesca Del; Simeoni, Francesco; Tamburro, Roberto; Falerno, Ilaria; Vignoli, Massimo

doi:10.1016/j.yasa.2020.07.004

Cited by 1 publication

(2 citation statements)

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“…However, CT allows better evaluation of the extent of the lesion than US and fluoroscopy [ 24 ], as well as in lesions surrounded by gas as opposed to in US [ 1 , 24 ]. Moreover, CT is a more sensitive technique to examine for metastases compared to fluoroscopy and conventional radiology [ 7 , 27 ]. The results of our study show that FNAB reached the final diagnosis in 69.4% of the cases versus 95.2% of TCB with a general sensitivity, accuracy and PPV of 67.7%, 67.7% and 100%, respectively, for FNAB and of 96.7%, 95.2% and 98.3%, respectively, for TCB.…”

Section: Discussionmentioning

confidence: 99%

“…In the present study, the patients were in sternal recumbency; however, if needed after the whole body CT for tumor staging, the position can be changed to a lateral recumbency to facilitate the biopsy sampling. It is important to avoid the study in lateral recumbency from the beginning to avoid lung collapse and consequent metastases being missed [ 27 ]. Changing the position of the patient also affect the time of the study which become longer because must be restarted from the beginning.…”

Section: Discussionmentioning

confidence: 99%

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Clinical Value of CT-Guided Fine Needle Aspiration and Tissue-Core Biopsy of Thoracic Masses in the Dog and Cat

Vignoli

Tamburro

Felici

et al. 2021

Animals

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Diagnosis of thoracic lesions on the basis of history and physical examination is often challenging. Diagnostic imaging is therefore of paramount importance in this field. Radiology has traditionally been considered the diagnostic procedure of choice for these diseases. Nevertheless, it is often not possible to differentiate inflammatory/infectious lesions from neoplastic diseases. A correct cytological and histopathologic diagnosis is therefore needed for an accurate diagnosis and subsequent prognostic and therapeutic approach. In human medicine, Computed Tomography (CT) and CT-guided biopsy are used in the presence of lesions which are not adequately diagnosed with other procedures. In the present study, thoracic lesions from 52 dogs and 10 cats of different sex, breed and size underwent both CT-guided fine-needle aspiration (FNAB) and tissue-core biopsy (TCB). Clinical examination, hematobiochemical analysis and chest radiography were performed on all animals. In this study, 59 of 62 histopathological samples were diagnostic (95.2%). Cytology was diagnostic in 43 of 62 samples (69.4%). General sensitivity, accuracy and PPV for FNAB and TCB were 67.7%, 67.7% and 100% and 96.7%, 95.2% and 98.3%, respectively. Combining the two techniques, the overall mean accuracy for diagnosis was 98.4%. Nineteen of 62 cases showed complications (30.6%). Mild pneumothorax was seen in 16 cases, whereas mild hemorrhage occurred in three cases. No major complications were encountered. CT-guided FNAB cytology can be considered a useful and reliable technique, especially for small lesions or lesions located close to vital organs and therefore dangerous to biopsy in other way.

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