TrmnE is MUCH CONTROVERSY about which is the most beneficial type of solution for intravenous infusion during general anaesthesia and major operation, and what its volume should be. Probably the most widely used is lactated Ringer's solut/on 1 which often is given in large anaounts to maintain electrolyte balance and both intravascular and extracellular fluid volumes. A major disadvantage of this solution is that the exogenous lactate does not supply energy as readily as glucose. Without exogenous glucose, the body is forced to mobilize glycogen, lipid, and protein, for the production of adenosine triphosphate (ATP). To explore the effects of commonly used infusions, we studied three groups of patients who received different solutions and a (control) group to whom none was given, during abdominal operations and for two hours postoperatively. The parameters studied included energy substrates, electrolytes, oxygen concentration in the blood and acid-base variables.