Whole cell microbial transformation in cloud point system

Wang, Zhilong; Xu, Jian‐He; Chen, Daijie

doi:10.1007/s10295-008-0345-6

Cited by 35 publications

(17 citation statements)

References 82 publications

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“…The expensive phase-forming components and the inconvenient downstream process of aqueous two-phase system are the main obstacles to its industrial application [17,30]. CPS combines the advantage of water-organic solvent two-phase system (inexpensive phase-forming components) and the advantage of aqueous two-phase system (biocompatibility at relatively higher polarity) [11,12]. However, a strip of nonvolatile organic compounds from the nonionic surfactant in the downstream process is very challengeable [14].…”

Section: Discussionmentioning

confidence: 99%

“…Recently, extractive microbial transformation in CPS has also been exploited in our previous work [5,10]. The main advantages of extractive microbial transformation in CPS include more biocompatible comparison to that of water-organic solvent two-phase system and more cheap in phase-forming components comparison to that of aqueous two-phase system [11,12]. However, stripping of organic product from nonionic surfactant in a microbial transformation broth is very challengeable [13,14].…”

Section: Introductionmentioning

confidence: 97%

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A Closed Concept of Extractive Whole Cell Microbial Transformation of Benzaldehyde into l-Phenylacetylcarbinol by Saccharomyces cerevisiae in Novel Polyethylene-Glycol-Induced Cloud-Point System

Wang

Liang

et al. 2009

Appl Biochem Biotechnol

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Extractive microbial transformation of benzaldehyde into L-phenylacetylcarbinol (L-PAC) by Saccharomyces cerevisiae (Baker's yeast) has been carried out in a novel polyethylene-glycol-induced cloud-point system (PEG-CPS). The extractive microbial transformation in the PEG-CPS and a downstream process for stripping of the product from the microbial transformation broth with microemulsion extraction are demonstrated. The results indicate that the PEG-CPS maintains the advantage of CPS for in situ extraction of polar product in the microbial transformation. At the same time, the utilization of hydrophilic nonionic surfactant in the PEG-CPS is favorable for stripping of product from the nonionic surfactant in the microbial transformation broth by Winsor I microemulsion extraction. Thus, a closed concept of in situ extraction of polar product in microbial transformation and its downstream process of product recovery are fulfilled at the same time.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 97%

A Closed Concept of Extractive Whole Cell Microbial Transformation of Benzaldehyde into l-Phenylacetylcarbinol by Saccharomyces cerevisiae in Novel Polyethylene-Glycol-Induced Cloud-Point System

Wang

Liang

et al. 2009

Appl Biochem Biotechnol

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“…In this case, non-ionic surfactants increase ABE solvent biocompatibility with bacteria by means of cloud-point extraction [145]. Surfactants are normally classified by the nature of their head group as cationic, anionic, non-ionic and dual charge.…”

Section: Non-ionic Surfactantsmentioning

confidence: 99%

Quest for sustainable bio-production and recovery of butanol as a promising solution to fossil fuel

Maiti

Gallastegui

Brar

et al. 2015

Int. J. Energy Res.

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Summary Biobutanol has conventionally been generated by fermentation of carbohydrates derived from biomass (starch or sugar‐based feedstock, such as corn) using Clostridia strains (mainly C. beijerinckii and C. acetobutylicum) under anaerobic conditions in batch mode. Under these premises, it has been tough for the acetone–butanol–ethanol fermentation to compete with petro‐butanol production from an energy efficiency and material consumption standpoint. Challenges for butanol production from biomass comprised high cost of feedstock, scarcity of hyper‐butanol producing bacteria and low butanol yield, volumetric productivity and titre, leading to high water usage and separation‐purification costs. This article is an up‐to‐date review on several under explored sections, such as optimization of fermenter feed, microbial culture responsible for solvent production (co‐culture techniques and electro‐biochemical process), latest recovery techniques and the studies integrating in situ continuous fermentation processes. Biobutanol refinery way forward should build upon the use of low‐cost lignocellulosic matter and zero cost organic wastes and by‐products from food, agriculture, forestry, fermentation and paper industries as feedstock; optimized fermentation of such diversified feed with appropriate hyper‐butanol producing strains in biofilm reactors and integration of fermentation step with hybrid high butanol‐selective recovery techniques. Copyright © 2015 John Wiley & Sons, Ltd.

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“…Therefore, the CP is an important property for selecting NSs in the formulation of such disperse systems. Analog to the log P is chosen as a parameter for an organic solvent, and the cloud point of a nonionic surfactant may act as a criterion for selecting NSs [7]. For example, in remediation technology of contaminated soil, generally the nonionic surfactants with higher CP temperatures are employed to solubilize organic compounds in aqueous solution in order to improve the biocompatibility of these compounds [8].…”

Section: Introductionmentioning

confidence: 99%