Widened QRS interval and left ventricular systolic depression after propafenone and promazine exposure

A subcutaneous finger cardioverter-defibrillator system removal under local anesthesia

“…In these patients, in addition to the ICD, devices can be needed to facilitate cardioversion. This case focuses on the subcutaneous Finger lead removal performed without complications and under local anesthesia and on the importance of a collaborative vision of a multi-disciplinary treatment team [69] for patient's safety.…”

Endocarditis due to Acinetobacter baumannii

“…Diverse mechanisms of resistance of these organisms limit the available therapeutic agents, make the infection difficult to treat, and are associated with a greater risk of death [41]. In the emerging scenario of concomitant problems and diseases [42][43][44][45][46][47][48][49][50][51][52][53][54][55][56],intensivists should be familiar with available drugs, environmental epidemiology and patient factors [40,53] as well as with new emerging findings regard use of cardiovascular drugs [42][43][47][48][51][52]. We present a case of an infective endocarditis in a 69-year-old Italian woman.…”

Regulator of G-protein signaling 2 (RGS2) in cardiology and oncology

“…Research suggests that myostatin stimulates expression of RGS2 preventing cardiac hypertrophy and heart failure [35]. The role of RGS2 in cardiovascular system inflammation and in cancer [36][37][38] is still under observation and can be an interesting link to cardio-oncology while new findings are emerging with regard to the use of cardiovascular drugs [55,68,69,73,74,84]. In primary human airway smooth muscle cells, glucocorticoid/ long-acting β (2)-adrenoceptor agonist (LABA) combination synergistically induces the expression of RGS2 reduced intracellular free calcium flux elicited by histamine, methacholine, leukotrienes, and other spasmogens [37].…”