Wild fauna as a probable animal reservoir for Trypanosoma brucei gambiense in Cameroon

Njiokou, Flobert; Laveissière, Claude; Simo, Gustave; Nkinin, Stephenson W.; Grébaut, Pascal; Cuny, G; Herder, Stéphane

doi:10.1016/j.meegid.2005.04.003

Cited by 127 publications

(109 citation statements)

References 18 publications

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“…T he trypanosome infection rates in the domestic animals detected with QBC (3.8 %) corroborates previous finding by other authors in domestic animals (Scott et al, 1983;Noireau et al, 1986;Asonganyi et al, 1986Asonganyi et al, , 1990, and in wild animals (KomoinOka et al, 1984;Njiokou et al, 2006). The proportion of animals LiTat 1.3 CATT-positive were generally higher than for QBC, suggesting that a high proportion of the animals had been in contact with T. b. gambiense or other parasites of the T. brucei s.l complex, or even T. congolense which also give positive results with LiTat 1.3 CATT (Noireau et al, 1986).…”

Section: Discussionsupporting

confidence: 88%

“…Thus, isoenzymes (Gibson et al, 1978;Scott et al, 1983;Nkinin et al, 2002) and amplification of sequences of microsatellite DNA Jamonneau et al, 2004;Njiokou et al, 2006) specific to T. b. gambiense have confirmed the presence of this parasite in pigs and wild animals. A program for the study of animal reservoirs of sleeping sickness was initiated in Cameroon in 1999; PCR has allowed the identification of many different wild animals (primates, antelopes, rodents and small carnivores) infected with T. b. gambiense group 1 in active foci of sleeping sickness in Cameroon Njiokou et al, 2006). In non-sleeping sickness zones, the same animal types did not have T. b. gambiense, although they were infected by other trypanosomes of the species complex T. brucei s.l.…”

Section: Introductionmentioning

confidence: 90%

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Domestic animals as potential reservoir hosts ofTrypanosoma brucei gambiensein sleeping sickness foci in Cameroon

Njiokou

Nimpaye

Simo³

et al. 2010

Parasite

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Summary :An explanation of the endemic nature and/or the resurgence of Human African Trypanosomiasis (HAT) in the historic foci in West and Central Africa may be the existence of an animal reservoir. In some HAT foci, pigs were found infected by Trypanosoma brucei gambiense but the implication of the other domestic animals was not quite evaluated. This study aims to determine the prevalence of T. b. gambiense in domestic animal species (goat, sheep, pig and dog) commonly found in the four active HAT foci in Cameroon (Bipindi, Fontem, Campo and Doumé). Blood samples were collected from 307 pigs, 264 goats, 267 sheep and 37 dogs and used for parasitological (QBC), immunological (LiTat 1.3 CATT) and molecular (PCR) analyses. QBC detected trypanosomes in 3.88 % domestic animals while 22.7 % were sero-positive with LiTat 1.3 CATT tests. Of the 875 animals analysed, 174 (19.88 %) harboured T. brucei s.l. DNA, found in each of the four types of animal and in the four localities. The infection rate significantly differed among the animal species (p < 0.0001) and localities (p < 0.0001). The PCR also revealed T. b. gambiense group 1 DNA in 27 (3.08 %) domestic animals. The specific infection rates were as follows: sheep (6.74 %), goats (3.08 %), pigs (0.32 %) and dogs (0 %). T. b. gambiense was found in 8 (3.92 %) animals from Bipindi, 15 (4.83 %) from Campo, 4 (2.59 %) from Fontem-Center and none from Doumé. The infection rates significantly differed between the localities, and correlated with the intensity of HAT transmission in the foci. Résumé

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Section: Discussionsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 90%

Domestic animals as potential reservoir hosts ofTrypanosoma brucei gambiensein sleeping sickness foci in Cameroon

Njiokou

Nimpaye

Simo³

et al. 2010

Parasite

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“…Out of four genera of protozoan parasites reported from pangolins, Eimeria was intestinal parasite and Trypanosoma and Toxoplasma were haemo-protozoan parasite and the site of parasitism for Piroplasma in pangolins could not be found from available literature (Rewell 1950;Kageruka and Willaert 1971;Else and Colley 1976;Njiokou et al 2004Njiokou et al , 2006Jirku et al 2013). Clark et al (2009) reported death of pangolin (M. javanica) secondary to gastrointestinal coccidiosis.…”

Section: Resultsmentioning

confidence: 99%

Check list of parasites and bacteria recorded from pangolins (Manis sp.)

Mohapatra¹,

Panda²,

Nair³

et al. 2015

J Parasit Dis

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Sound knowledge on parasite fauna of pangolins is crucial for evaluation of their health status. In the present review, a checklist of 34 genera of parasites and bacteria, including 4 genera of protozoan, 13 genera of helminthes, 8 genera of ticks, 2 genera of mites and 7 genera of bacteria reported from pangolins was compiled and their zoonotic potential were discussed. The aim of this checklist is to underline the information gap and to provide a reference list of parasites and bacteria known for pangolins to assist in their further investigation.

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“…Animals play a less important part, but pigs and some wild animal species have been reported as being a reservoir. 47,43 …”

Section: Vector and Parasitementioning

confidence: 99%

Human African Trypanosomiasis

Brun

Blum

2012

Infectious Disease Clinics of North America

141

230

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Wild fauna as a probable animal reservoir for Trypanosoma brucei gambiense in Cameroon

Cited by 127 publications

References 18 publications

Domestic animals as potential reservoir hosts ofTrypanosoma brucei gambiensein sleeping sickness foci in Cameroon

Domestic animals as potential reservoir hosts ofTrypanosoma brucei gambiensein sleeping sickness foci in Cameroon

Check list of parasites and bacteria recorded from pangolins (Manis sp.)

Human African Trypanosomiasis

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