Wireless Biological Electronic Sensors

Cui, Yue

doi:10.3390/s17102289

Cited by 15 publications

(8 citation statements)

References 82 publications

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“…[9,[11][12][13] The integration of these biosensor technology with IoT (Internet of things) enables the possibility to automatically transmit data by wireless network modalities (e.g., cellular data service, Wi-Fi, Bluetooth) for a cloud heath database. [14][15][16] However, the need to execute PCR amplification to reliably detect the virus make a limitation in the development of low-cost and portable systems because of the need of thermal module and optical apparatus that cannot be easily integrated in portable systems. Therefore, PoCTs able to perform molecular analysis of SARS-CoV-2 RNA needs innovative biotechnologies for the genetic detection that simplify the detection avoid the many analytical steps required by the conventional PCR that increases the complexity and costs of the final system.…”

Section: Introductionmentioning

confidence: 99%

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PCR‐Free Innovative Strategies for SARS‐CoV‐2 Detection

Calorenni,

Leonardi,

Sciuto

et al. 2023

Adv Healthcare Materials

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The pandemic outbreak caused by SARS‐CoV‐2 coronavirus brought a crucial issue in public health causing up to now more than 600 million infected people and 6.5 million deaths. Conventional diagnostic methods are based on quantitative reverse transcription polymerase chain reaction (RT‐qPCR assay) and immuno‐detection (ELISA assay). However, despite these techniques have the advantages of being standardized and consolidated, they keep some main limitations in terms of accuracy (immunoassays), time/cost consumption of analysis, the need for qualified personnel, and lab constrain (molecular assays). There is crucial the need to develop new diagnostic approaches for accurate, fast and portable viral detection and quantification. Among these, PCR‐free biosensors represent the most appealing solution since they can allow molecular detection without the complexity of the PCR. This will enable the possibility to be integrated in portable and low‐cost systems for massive and decentralized screening of SARS‐CoV‐2 in a point‐of‐care (PoC) format, pointing to achieve a performant identification and control of infection. In this review, the most recent approaches for the SARS‐CoV‐2 PCR‐free detection are reported, describing both the instrumental and methodological features, and highlighting their suitability for a PoC application.

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Section: Introductionmentioning

confidence: 99%

“…[ 9,11–13 ] The integration of these biosensor technology with IoT (Internet of things) enables the possibility to automatically transmit data by wireless network modalities (e.g., cellular data service, Wi‐Fi, Bluetooth) for a cloud heath database. [ 14–16 ]…”

Section: Introductionmentioning

confidence: 99%

PCR‐Free Innovative Strategies for SARS‐CoV‐2 Detection

Calorenni,

Leonardi,

Sciuto

et al. 2023

Adv Healthcare Materials

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“…Among these challenges are the identification of appropriate cell lines, the development of a reliable and effective manufacturing method, and the guaranteeing of the requisite quality attributes in the final product. Biosimilar monitoring is essential for overcoming these obstacles because it gives real-time data and insights into the process, allowing researchers and manufacturers to make well-informed decisions and improve the development and manufacturing processes [8]. Biosimilars bring unique challenges and opportunities for pharmaceutical companies implementing Cyber-Physical Systems.…”

Section: Introductionmentioning

confidence: 99%

Wireless Antenna Sensors for Biosimilar Monitoring Toward Cyber-Physical Systems: A Review of Current Trends and Future Prospects

Haq,

Rehman,

Alhulayyil

et al. 2023

IEEE Access

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The integration of wireless antenna sensors for cyber-physical systems has become increasingly prevalent in various biosimilar applications due to the escalating need for monitoring techniques that are efficient, accurate, and reliable. The primary objective of this comprehensive investigation is to offer a scholarly examination of the present advancements, challenges, and potentialities in the realm of wireless antenna sensor technology for monitoring biosimilars. Specifically, the focus will be on the current state of the art in wireless antenna sensor design, manufacturing, and implementation along with the discussion of cyber security trends. The advantages of wireless antenna sensors, including increased sensitivity, real-time data gathering, and remote monitoring, will next be discussed in relation to their use in a variety of biosimilar applications. Furthermore, we will explore the challenges of deploying wireless antenna sensors for biosimilar monitoring, such as power consumption, signal integrity, and biocompatibility concerns. To wrap things off, there will be a discussion about where this subject is headed and why collaborative work is essential to advancing wireless antenna sensor technology and its applications in biosimilar monitoring. Providing an in-depth overview of the present landscape and potential developments, this article aims to be an asset for academics and professionals in the fields of antenna sensors, biosimilar development, wireless communication technologies, and cyber physical systems.INDEX TERMS Cyber-physical systems, wireless antenna sensors, biosimilar monitoring, real-time data acquisition.

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“…Wirelessly controlled electronic devices have been developed for a variety of applications, including (but not limited to) antennae, 43,44 drug delivery devices, 45–53 light emitting diodes (enabling optogenetic applications) 54–58 and sensors (perhaps the most popular application) 59–67 due to their potential integration in and control of other devices (e.g. wheel chairs, 68 drug delivery devices 55,69 etc.).…”

Section: Introductionmentioning

confidence: 99%

Wirelessly triggered bioactive molecule delivery from degradable electroactive polymer films

Ashton

Appen

Fırlak

et al. 2020

Polymer International

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The development of stimuli‐responsive drug delivery systems offers significant opportunities for innovations in industry. It is possible to produce polymer‐based drug delivery devices enabling spatiotemporal control of the release of the drug triggered by an electrical stimulus. Here we describe the development of a wireless controller for drug delivery from conductive/electroactive polymer‐based biomaterials and demonstrate its function in vitro. The wireless polymer conduction controller device uses very low power, operating at 2.4 GHz, and has a supply voltage controller circuit which controls electrical stimulation voltage levels. The computer graphical user interface program communicates with the controller device, and it receives device information, device status and temperature data from the controller device. The prototype of the wireless controller system can trigger the delivery of a drug, dexamethasone phosphate, from a matrix of degradable electroactive polymers. Furthermore, we introduce the application of in silico toxicity screening as a potentially useful method to facilitate the design of non‐toxic degradable electroactive polymers for a multitude of biotechnological applications, addressing one of the key commercial challenges to biomaterial development, in accordance with ‘safe by design’ principles. © 2020 The Authors. Polymer International published by John Wiley & Sons Ltd on behalf of Society of Industrial Chemistry.

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Wireless Biological Electronic Sensors

Cited by 15 publications

References 82 publications

PCR‐Free Innovative Strategies for SARS‐CoV‐2 Detection

PCR‐Free Innovative Strategies for SARS‐CoV‐2 Detection

Wireless Antenna Sensors for Biosimilar Monitoring Toward Cyber-Physical Systems: A Review of Current Trends and Future Prospects

Wirelessly triggered bioactive molecule delivery from degradable electroactive polymer films

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