Worsening renal function after transcatheter aortic valve replacement and surgical aortic valve replacement

Tobe, Akihiro; Tanaka, Akihito; Tokuda, Yoshiyuki; Nishi, Tetsuo; Miki, Yusuke; Fukui, Kenji; Ishii, Hideki; Usui, Akihiko; Murohara, Toyoaki

doi:10.1007/s00380-021-01778-2

Cited by 1 publication

(2 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Since in vitro and in vivo studies that relate blood biochemistry to TAV thrombosis are limited, in this section, we include results from both methods. Studies have confirmed the relationship between elevated D-dimer levels and valve thrombosis [51,52], additionally linking observed increased haemostasis-related biomarkers immediately after implantation to a transient occurrence that is not strictly tied to increased thrombin formation [53]. The aggregation of platelets in the neo-sinus may be responsible for the increased levels of thrombosis in this region.…”

Section: Blood Biochemistrymentioning

confidence: 82%

See 1 more Smart Citation

Transcatheter aortic valve thrombosis: a review of potential mechanisms

Raghav

Midha

Sharma

et al. 2021

J. R. Soc. Interface.

View full text Add to dashboard Cite

Transcatheter aortic valve (TAV) thrombosis has been recognized as a significant problem that sometimes occurs as early as within 30 days after valve implantation, leading to increased concerns of stroke and long-term valve durability. In this article, a critical summary of the relevant literature on identifying potential mechanisms of TAV thrombosis from the perspective of the well-known Virchow's triad, which comprises blood flow, foreign materials and blood biochemistry, is presented. Blood flow mechanisms have been the primary focus thus far, with a general consensus on the flow mechanisms with respect to haemodynamic conditions, the influence of TAV placement and expansion and the influence of coronary flow. Less attention has been paid to the influence of blood biochemistry and foreign materials (and related endothelial damage), with little consensus among studies with regards to platelet and/or microparticle levels post-TAV implantation. Finally, we discuss the future outlook for research with unanswered scientific questions.

show abstract

Section: Blood Biochemistrymentioning

confidence: 82%

“…Tobe et al [52] Perioperative baseline and peak D-dimer levels are lower in patients on anticoagulation (baseline: 0.5 IU ml −1 versus 1.1 IU ml −1 ; 2.4 IU ml −1 versus 5.2 IU ml −1 ).…”

Section: Foreign Materials and Endothelial Damagementioning

confidence: 99%