Wound Measurement

Wysocki, Annette B.

doi:10.1111/j.1365-4362.1996.tb03266.x

Cited by 36 publications

(18 citation statements)

References 36 publications

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“…sutures. We preferred incisional wound rather than excisional, because in case of the latter there is usually initial-lag-phase for reepithelization 4 . Sutures were removed on post-operative day 14 th .…”

Section: Resultsmentioning

confidence: 99%

The effect of prophylactic dose of a low molecular weight heparin on skin wound healing of rats

et al. 2009

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Purpose:To investigate the effect of prophylactic dose of a low molecular weight heparin, enoxaparin, on skin wound healing of rats. Methods: Forty rats were used for the study. Rats were randomly assigned to two equal groups. Experimental group received prophylactic dose of enoxaparin. Physiologic saline was administered to the control group. Parameters of wound healing of experimental and control groups were compared. For comparison of the groups in terms of fibrosis, vascularization, inflammation, epithelization, and tensile strength test (Newton). Mann-Whitney-U test was used because variables were categorical data (fibrosis, vascularization, inflammation and epithelization). Differences between groups were analyzed with independent samples t-test (tensile strength). Significance was set at p<0.05. Results: Skin wound of the experimental group presented tensile strength significantly decreased (p<0.001), histopathologic examination revealed a significant (p<0.001) delayed epithelization and decreased in fibrosis, vascularization, inflammation (p<0.001) in the experimental group. Conclusion: Enoxaparin delay wound healing by decreased inflammatory cells, fibroblast contents and their products (growth factors), and by promoted hemorrhage.

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Section: Resultsmentioning

confidence: 99%

The effect of prophylactic dose of a low molecular weight heparin on skin wound healing of rats

et al. 2009

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“…10,11 Most of those parameters are obtained by direct surface measurement and visual observation. Those methods, however, do not provide structural information below the wound surface and can be very subjective, bearing considerable interobserver variability, which heavily depends upon the observer's experience, wound condition, and treatment history.…”

Section: Introductionmentioning

confidence: 99%

Noninvasive assessment of cutaneous wound healing using ultrahigh-resolution optical coherence tomography

et al. 2006

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Ultrahigh-resolution optical coherence tomography (OCT) was used for noninvasive in vivo evaluation of the wound healing process. Cutaneous wounds were induced by 2.5-mm diameter full-thickness punch biopsies on the dorsal surface of seven mice. OCT imaging was performed to assess the structural characteristics associated with the healing process. The OCT results were compared to corresponding histology. Two automated quantitative analysis routines were implemented to identify the dermal-epidermal junction and segment the OCT images. Hallmarks of cutaneous wound healing such as wound size, epidermal migration, dermal-epidermal junction formation, and differences in wound composition were readily identified on the OCT images. Blister formation was also observed. Preliminary findings suggest OCT is a viable tool to noninvasively monitor wound healing in vivo.

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“…Parameters of wound healing include the area and depth of the wound, total time to heal, and rate of healing. These parameters are often difficult to evaluate objectively 5 ; therefore, we chose the eradication of amastigotes as our main biological end point for determining the duration of treatment.…”

Section: Commentmentioning

confidence: 99%

Treatment of Cutaneous Leishmaniasis With Photodynamic Therapy

Enk¹

2003

Arch Dermatol

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Wound Measurement

Cited by 36 publications

References 36 publications

The effect of prophylactic dose of a low molecular weight heparin on skin wound healing of rats

The effect of prophylactic dose of a low molecular weight heparin on skin wound healing of rats

Noninvasive assessment of cutaneous wound healing using ultrahigh-resolution optical coherence tomography

Treatment of Cutaneous Leishmaniasis With Photodynamic Therapy

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