Xanthogranulomatous Orchitis: Rare Case with Brief Literature Review

Abstract

Xanthogranulomatous reaction is uncommon non neoplastic reaction involving multiple organs, commonly kidney and gallbladder. Its rarely involve testicle. We report 69-year old man present to clinic with right testicular swelling for six month duration. Testicular markers within normal range. Us scrotum revealed right large avascular heterogeneous mass inside testicle. Right inguinal orchiectomy done and revealed Xanthogranulomatous orchitis.

Xanthogranulomatous orchitis: Review of the published work, and report of one case

“…Spermatic tract obstruction is either Mechanical obstruction, or functional obstruction, spermatic tact dysfunction in case of diabetes caused by neuropathy also play a role which is reported in 6 cases, 1 Mechanical obstruction of the spermatic tract was reported in 4 case of post prostatectomy in patients with xanthogranulomatous orchioepididymitis, 1 , 2 obstruction plays major role in pathogenesis but it is not a must, since there was a case reports that there is no clear cause for sperm flow obstruction like a case of XGO reported after intravesical BCG for case of bladder tumor following TURBT, 3 or there was also a case report that both XGO and seminoma occurred in same testis 4 …”

Xanthogranulomatous orchitis: case report of a rare condition

“…However, such findings are not specific to the xanthogranulomatous process and could be concomitant to a tumor (7). The diagnosis is challenging, as the condition can resemble bacterial orchitis, which improves with antibiotic therapy, malakoplakia with typical Michaelis-Gutmann bodies (3) and neoplasm with differences in tumor and immunohistochemical markers (8).…”

“…Due to the destructive effects of xanthogranulomatous orchitis, treatment should be aggressive, with radical orchiectomy (as performed in the present case), which could be partial in some cases. Antibiotic therapy for anaerobic bacteria is also important (8)(9)(10).…”

Xanthogranulomatous Orchitis Presenting as a Scrotal Mass in an Elderly Male: Malignancy or Mimicker?

“…However, it can also affect the liver, appendix, ovaries, vagina, bones, and urinary bladder. 1 It can rarely affect the prostate, epididymis, and testicle. Involvement of the testicles by xanthogranulomatous inflammation is rare and exact pathogenesis remains unknown.…”

“…Involvement of the testicles by xanthogranulomatous inflammation is rare and exact pathogenesis remains unknown. 1 Furthermore, xanthogranulomatous orchitis (XGO) mimics a testicular malignancy clinically as well as radiologically; pathological examination is essential for a confirmation and thorough histological examination is needed to rule out any coexistent malignancy. 2 …”