2019
DOI: 10.23736/s0375-9393.18.12406-0
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Xenon anesthesia for awake craniotomy: safety and efficacy

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Cited by 18 publications
(15 citation statements)
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References 49 publications
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“…Dilmen et al 38 concluded that blood pressure was higher in the MAC group during head frame fixation and incision, whereas higher in the SAS group during the intraoperative neurological assessment. Kulikov et al 36 used xenon anesthesia and found that 50% of patients experienced at least 1 hypertensive episode (systolic blood pressure > 150 mm Hg) during the incision and craniotomy phases.…”
Section: Other Outcomesmentioning
confidence: 99%
“…Dilmen et al 38 concluded that blood pressure was higher in the MAC group during head frame fixation and incision, whereas higher in the SAS group during the intraoperative neurological assessment. Kulikov et al 36 used xenon anesthesia and found that 50% of patients experienced at least 1 hypertensive episode (systolic blood pressure > 150 mm Hg) during the incision and craniotomy phases.…”
Section: Other Outcomesmentioning
confidence: 99%
“…In her study, Myasnikova V. showed that anesthesia with xenon at concentration of 48-55 % significantly reduced BIS down to 46-56 during ophthalmic surgery, however narcotic analgesics and nonsteroidal anti-inflammatory drugs (NSAIDs) were used throughout the surgery which could have an additional effect on BIS values [5]. In a study using xenon anesthesia in neurosurgery for craniotomy to remove brain neoplasms, the BIS index level was within safe range, but 70 % of the patients had epilepsy and were on anticonvulsants, while narcotic analgesics were also used during surgical treatment along with NSAIDs, which could alter the EEG pattern and BIS level [6]. Similar data were obtained in earlier works of other authors, where various techniques of monitoring the depth of hypnosis showed convincing results in xenon anesthesia, but had limitations such as age, concomitant use of narcotic analgesics, benzodiazepines, anticonvulsants in the perioperative period, or diseases that could affect the baseline EEG [7][8][9][10][11].…”
Section: Introductionmentioning
confidence: 99%
“…Xenon is an inert gas that has been used in clinical practice as an anesthetic for more than 70 years ( Maze and Laitio, 2020 ). Moreover, the safety of xenon has been verified through long-term clinical applications ( Kulikov et al, 2019 ). In recent years, studies have demonstrated the excellent neuroprotective effects of xenon at sub-anesthetic doses ( Metaxa et al, 2014 ; Yang et al, 2014 ; Lavaur et al, 2016a ).…”
Section: Introductionmentioning
confidence: 99%