Xenon Difluoride Dry Etching for the Microfabrication of Solid Microneedles as a Potential Strategy in Transdermal Drug Delivery (Small 27/2023)

Abstract

Solid Microneedles Despite the significance of microneedles for drug delivery, high‐cost, limited‐geometries, and complex fabrication are still hampering their expansion. Xenon difluoride (XeF2) dry etching precisely manufactures thousands of microneedles with tunable dimensions and geometries on a single patch. Confirming their penetration with skin models and numerical analyses, these microneedles hold significant potential for noninvasive, pain‐free, and effective drug delivery studies. More details can be found in article number 2206510 by Fatih Inci and co‐workers.