Y-chromosome STR haplotype profiling in the Korean population

Kim, Yung Jin; Shin, Dong Jik; Kim, Jung Min; Jin, Han Jun; Kwak, Kyoung Don; Han, Myun Soo; Choi, Sang Kyu; Kim, Wook

doi:10.1016/s0379-0738(00)00332-7

Cited by 22 publications

(9 citation statements)

References 2 publications

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“…Y-haplotypes constructed from the ten loci and the haplotype diversity value are also shown in Table 3. Allele and haplotype distributions were very similar to that previously reported for Koreans, which were analysed for seven Y-STR markers [20]. We identified 295 different haplotypes, and 279 were seen only once.…”

supporting

confidence: 83%

Y-Chromosome multiplexes and their potential for the DNA profiling of Koreans

Shin

Jin

Kwak

et al. 2001

International Journal of Legal Medicine

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We have developed four multiplex genotyping systems (GeneKin Y-STR multiplexes) using silver staining with allelic ladders for ten Y-chromosome STR markers (DYS19, DYS385, DYS388, DYS389I/II, DYS390, DYS391, DYS392, DYS393 and DXYS156Y), with a view towards the application of rapid and simple genotyping assay methods for DNA profiling. The GeneKin Y-STR multiplexes developed have followed the published nomenclature and ISFG guidelines for STR analysis. Allele and haplotype frequencies at these Y-STRs loci were analysed by PCR amplification using the GeneKin Y-STR multiplexes, followed by denaturing polyacrylamide gel electrophoresis in 316 unrelated males in the Korean population. A total of 295 different haplotypes were found, 279 of them being unique. Gene diversity ranged from 0.4026 at DYS391 to 0.9606 at DYS385. The haplotype diversity value (which is the same as the discrimination index) calculated from all ten loci combined was 0.9995, which is informative. Our results revealed that a set of ten Y-STRs can discriminate between most of the male individuals in the Korean population (discrimination capacity: 93.35%). The Y-STR multiplexes thus provide useful information for forensic analysis and paternity tests and can also be of great benefit for providing information not normally available from autosomal DNA systems.

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supporting

confidence: 83%

Y-Chromosome multiplexes and their potential for the DNA profiling of Koreans

Shin

Jin

Kwak

et al. 2001

International Journal of Legal Medicine

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“…Other remarks: Allelic and haplotype frequencies were grossly similar to those found in other East Asian populations [4,5],whilst at some loci the Han population were deviate from European population which previously have been studied [6][7][8]. Table 1 shows the allele frequencies distribution for each locus in the Xi'an Han ethnic group.…”

supporting

confidence: 69%

Y-chromosome STR haplotypes of Han ethnic group in Xi’an (NW China)

Wang

et al. 2003

Forensic Science International

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“…Gene diversities of the three Y STR loci in this study were observed to be 0.63 in DYS390, 0.70 in DYS392 and 0.66 in DYS393. These values were similar to the results of Kim et al (2001). The allelic frequencies and gene diversities of DYS390, DYS392 and DYS393 in Koreans were similar to those of Chinese in Taiwan, but were different from Italians (Table 4).…”

Section: Resultssupporting

confidence: 85%