Yeasts and yeast-based products in poultry nutrition

Impact of dietary-nucleotides and Saccharomyces cerevisiae-derivatives on growth-performance, antioxidant-capacity, immune-response, small-intestine histomorphometry, caecal- Clostridia , and litter-hygiene of broiler-chickens treated with florfenicol

“…In the current study, the growth performance parameters (BW, BWG, and FCR) were significantly improved in broiler chickens fed yeast-derived components (beta-1,3;1,6 glucans, mannans, and nucleotides) and birds treated with florfenicol in water compared with the control group. Previous studies have discussed that under challenging field conditions, supplementing yeast derivatives and antibiotics in diets protected the intestinal tract from the colonization of pathogens, enhanced FCR, and improved birds’ health [ 8 , 10 , 36–38 ]. In addition, NutriFix® contains high concentrations of nucleotides, which may contribute to improved performance since yeast nucleotides have been shown to increase chicken growth in terms of average daily gain and FCR and are beneficial for broilers immunity and nutrient utilization [ 11 , 39 , 40 ].…”

“…However, no significant improvements in carcass attributes were recorded between the experimental groups. According to certain studies, dietary yeast-derived products boosted the yields of broiler chicken carcasses, including the weights of the breast, thigh, and drumstick [ 6 , 36 ]. However, numerous research [ 42 , 43 ] showed no significant variation in carcass characteristics.…”

“…Those findings could be attributed to the role of dietary inclusion of yeasts ( S. cerevisiae ) in the enhancement of nutrient bioavailability and boosting the enzymatic activity such as alanine aminotransferase, aspartate aminotransferase, creatine phosphokinase, and lactate dehydrogenase, which promote food utilization [ 46 ]. Fathima et al [ 36 ] stated that dietary yeast is a rich source of protein, minerals, and vitamins and meets the amino acid demands of broilers, which could replace soybean and fish meals. Furthermore, NutriFix® supplementation showed significant hypolipidemic action.…”

“…Paraprobiotics refer to non-living microbial cells or cell fragments that are immunologically active and thus beneficial to the host. Postbiotics are the soluble substances released by probiotic microbes [ 36 ]. The results of the current study suggest that supplementing with NutriFix® can significantly improve the immunosuppressive effects of florfenicol by enhancing several parameters of the leukogram.…”

“…It has been known since 1964 that mannans produced from yeast cell walls have immunogenic properties [ 52 ]. Additionally, β-glucans can stimulate the innate immune system, which leads to lymphocyte activation and stimulation of the adaptive immune system [ 36 , 53 ].…”