Yellow chromonychia after ascorbic acid application

Gregoriou, Stamatis; Kazakos, C.; Rigopoulos, Dimitrios

doi:10.1111/j.1365-2230.2010.04000.x

Cited by 10 publications

(3 citation statements)

References 2 publications

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“…Chromonychia is an aspecific pigmentation phenomenon of the nail plate, described as a side effect of chemotherapy , antimycotic ointment application , use of formaldehyde‐containing nail hardener , Pseudomonas infections , use of angiotensin II receptor blockers , and systemic lupus erythematosus .…”

Section: Discussionmentioning

confidence: 99%

Orange‐Brown Chromonychia and Kawasaki Disease: A Possible Novel Association?

Tessarotto

Rubin

Bonadies

et al. 2015

Pediatric Dermatology

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A 4-year-old girl with clinical and laboratory signs of Kawasaki disease (KD) was hospitalized and given intravenous immunoglobulin plus aspirin therapy, with rapid defervescence and clinical improvement, and was discharged 48 hours after admission. At the time of her follow-up echocardiography on day 14, orange-brown pigmentation of the nail beds was noticed and confirmed with dermoscopy. No clear association between KD and orange-brown chromonychia has been demonstrated, although reports and case series suggest a possible link between these two entities. We suggest that this particular finding might be encompassed in late (subacute) changes of extremities as part of KD diagnostic criteria.

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Section: Discussionmentioning

confidence: 99%

Orange‐Brown Chromonychia and Kawasaki Disease: A Possible Novel Association?

Tessarotto

Rubin

Bonadies

et al. 2015

Pediatric Dermatology

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“…For example, a case of yellow nail discoloration, known as yellow chromonychia, was reported due to the use of a galenic topical preparation containing ascorbic acid and miconazole nitrate, intended for preventing nail fungal infections. The discolored nails typically exhibited a border near the cuticle, and discontinuation of the cream for 2 months resolved the issue [40,52]. In addition, excessive use of a nail file in combination with amorolfine nail lacquer can lead to specific nail plate changes known as "amorolfine nails," characterized by thinning of the distal nail plate and reddening of the nail bed [40,53].…”

Section: Internal Exposomal Factors Nutritionmentioning

confidence: 99%

Exposome Impact on Nail Health

Prudkin,

Cedirian,

Santamaria

et al. 2024

Skin Appendage Disord

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Background: The nail unit is a complex system with various components, each serving distinct functions. The exposome, encompassing external and internal factors such as UV radiation, air pollution, dietary habits, and cosmetic product usage, substantially influences nail health and can lead to premature nail aging. Summary: Internal and external exposomal factors can impact differently on nail health, inducing a variety of different clinical conditions. Effective therapeutic strategies exist, but a comprehensive understanding of how the exposome affects nails is lacking. This article aims to bridge this knowledge gap by exploring the relationship between the exposome and nail health, emphasizing it as a central focus of our analysis. Key Messages: (1) The exposome, comprising various external and internal factors, may significantly influence nail health negatively, leading to premature nail aging. (2) Different nail conditions may arise due to the exposomal influence on nails. (3) Understanding the exposome’s impact on nail health is crucial for developing solutions to mitigate negative effects and improve overall nail well-being.

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“…Yellow discoloration of the nails has been reported secondary to repeated exposure to deep red nail polishes and also as a result of long‐term use of a topical 1% ascorbic acid preparation . These exogenous causes can mimic onychodystrophy, but the sparing of new growth at the proximal nail fold can be a clue to the exogenous nature of the discoloration.…”

Section: Othermentioning

confidence: 99%

Fifty shades of yellow: a review of the xanthodermatoses

2015

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The xanthodermatoses consist of a heterogeneous group of cutaneous disorders characterized by the macroscopic yellow hue seen on examination. This hue is attributable to the chemical structure of the accumulating substances within the skin or surrounding tissues. The most common culprits are lipids (cholesterol and triglycerides), elastin, and bilirubin. Exogenous sources of yellow pigment include yellow dyes (including hennas) and metal salts. This article will focus on recognition of these entities, classified in terms of morphology and the site of initial eruption, in order to support the recognition and diagnosis of these widely variable conditions.

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Yellow chromonychia after ascorbic acid application

Cited by 10 publications

References 2 publications

Orange‐Brown Chromonychia and Kawasaki Disease: A Possible Novel Association?

Orange‐Brown Chromonychia and Kawasaki Disease: A Possible Novel Association?

Exposome Impact on Nail Health

Fifty shades of yellow: a review of the xanthodermatoses

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