Yerba Mate Consumption Effect on the Total Concentration of Creatine Phosphokinase in Healthy Volunteers from the Age of 50

Abstract

This preliminary study investigated for the first time the effect of roasted yerba mate (Ilex paraguariensis A. St. Hil.) tea on total creatine phosphokinase (CPK) in volunteers from the age of 50 years. Volunteers were randomly assigned to intervention (n = 3) and control (n = 3) groups. Treated subjects consumed mate tea for 28 days (500 mL/daily) and were submitted to five blood collection taken at intervals of seven days. It was observed a poor correlation between CPK level and yerba mate consumption. Results were also analyzed through cluster and principal component analyses. Treated and not treated subjects were not grouped into independent clusters which agreed with correlation analysis. Principal component analysis conferred partial discriminatory information about non-treated and treated groups. This study did not identify any influence of yerba mate consumption on total CPK concentration in physiological conditions. Larger sample studies should be addressed to detect significant small physiological variations in CPK values.