Yonder: Primary aldosteronism, artificial intelligence, irritable bowel syndrome, and financial toxicity

Abstract

Primary aldosteronism. Hypertension is bread-and-butter work for GPs and primary aldosteronism (PA), also known as Conn's syndrome, is the most common cause of secondary hypertension. Despite the high prevalence in primary care GPs rarely screen for PA, and a recent Australian study sought to ask why this was the case. 1 They found that while GPs had been educated about PA, they found it challenging to explain it to patients and were uncertain about how to screen patients who were already taking antihypertensive medications. Most viewed the screening process to be practical and inexpensive, and found it inconvenient to alter antihypertensive medications before screening to allow for easier interpretation of the aldosterone-to-renin ratio. The authors suggest that most of these practical barriers could be addressed by relatively simple educational and practice modifications to increase PA screening rates and optimise detection.

Education as a cure for nostalgia

“…Ahmed Rashid as usual samples a smorgasbord of practice-relevant wisdom: primary aldosteronism, artificial intelligence, irritable bowel syndrome, and financial toxicity are on the menu. 6 Wisdom is located both in our cells and our society, a point that Tim Senior makes when he asks, 'Where do diseases live?' 'It seems an odd question, but perhaps an important one, because we need to find a disease in order to treat it [...] If we don't recognise the location correctly, we end up treating poverty with statins.'…”

From the Perspective of Computer Engineering: Research on Digestive Diseases based on Bioinformatics and Genetic Genetics

“…Using a feedback artificial neural network designed for a certain problem and giving full play to the high-speed computing ability of the computer, the optimal solution may be found quickly. This technology can be applied in clinical medicine to detect the pathogenesis of gastroenterologyneuroscience [1][2][3][4][5].…”