Introduction:Vaginal agenesis may present as a single defect in development or associated with other anomalies. It is usually associated with Mayer-Rokitansky-Kuster-Hauser (MRKH) and Androgen Insensitivity Syndromes (AIS). The incidence is about 1 in 4000-5000 live female births. This is a case series of six cases of vaginoplasties performed by three varied surgical techniques over a period of two years, with a follow up. Cases: A comparison of three techniques of vaginoplasties was done. Six total cases were included-three cases using modified McIndoe's technique with amnion graft, two using split thickness skin graft and one by Laparoscopic Peritoneal Pull through technique. Patients were followed up meticulously over the course of two years and results were recorded. The comparison scoring was done based on relative ease of the operative procedure, pain experienced, vaginal depth on follow up, uptake of graft and sexual satisfaction in the married females. Result: Despite new techniques of vaginoplasty advancing over the years such as laparoscopic approaches and use of different materials as grafts, vaginoplasty with amnion graft is stillpreferredfor the treatment of vaginal agenesis.The technique is simple and safe and provides a satisfactory and functional vagina in majority of the patients.