2024
DOI: 10.1186/s13062-024-00566-y
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YTHDF2 promotes anaplastic thyroid cancer progression by activating the DDIT4/AKT/mTOR signaling pathway

Bao Dai,
Lei Xu,
Shikuo Rong
et al.

Abstract: Background RNA methylation, an important reversible post-transcriptional modification in eukaryotes, has emerged as a prevalent epigenetic alteration. However, the role of the m6A reader YTH domain family 2 (YTHDF2) has not been reported in anaplastic thyroid cancer (ATC) and its biological mechanism is unclear. Methods The relationship between YTHDF2 expression and ATC was determined using data sets and tissue samples. A range of analytical techni… Show more

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