Yttrium-90 microsphere radioembolisation for unresectable hepatocellular carcinoma

Abdel‐Rahman, Omar; Elsayed, Zeinab

doi:10.1002/14651858.cd011313

Cited by 4 publications

(4 citation statements)

References 45 publications

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“…In addition to the high concordance among monozygotic twins compared with dizygotic twins with PBC, the strong association with human leukocyte antigen alleles, which vary by ethnicity, supports a genetic cause of inherited risk . Despite progress, only an estimated 15% of the variability of the disease has been accounted for by genetic studies .…”

Section: Etiology Of Primary Biliary Cholangitismentioning

confidence: 99%

“…(10)(11) In addition to the high concordance among monozygotic twins compared with dizygotic twins with PBC (5) , the strong association with human leukocyte antigen alleles, which vary by ethnicity, supports a genetic cause of inherited risk. (12)(13)(14)(15)(16)(17)(18)(19)(20) Despite progress, only an estimated 15% of the variability of the disease has been accounted for by genetic studies. (21) Environmental risks have been suggested by several large case-control cohort studies that have found associations with urinary tract infections, reproductive hormone replacement, nail polish, and past cigarette smoking.…”

Section: Preamblementioning

confidence: 99%

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Primary Biliary Cholangitis

et al. 2019

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Section: Etiology Of Primary Biliary Cholangitismentioning

confidence: 99%

Section: Preamblementioning

confidence: 99%

Primary Biliary Cholangitis

et al. 2019

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“…However, surgical resection is only suitable for early‐stage patients with well‐preserved liver function . In the majority (>70%) of HCC patients, the cancer has progressed to stages that make them ineligible for surgical resection or liver transplantation at the time of presentation and diagnosis …”

Section: Current Treatment Modalities For Unresectable (Intermediate mentioning

confidence: 99%

“…8,15,16,18 In the majority (>70%) of HCC patients, the cancer has progressed to stages that make them ineligible for surgical resection or liver transplantation at the time of presentation and diagnosis. 8,[19][20][21][22] For patients with unresectable intermediate-stage HCC (ie, BCLC stage B disease), transarterial chemoembolisation (TACE)-a type of locoregional therapy-is the first line of treatment recommended as per AASLD and EASL guidelines. Transarterial therapies take advantage of the fact that hepatic tumours receive their blood supply almost exclusively from the hepatic artery.…”

Section: Current Treatment Modalities For Unresectable (Intermediatmentioning

confidence: 99%

Treatment options for unresectable HCC with a focus on SIRT with Yttrium-90 resin microspheres

et al. 2017

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To identify relevant publications, the PubMed database was queried using one or more of the following search terms alone or in combination with Boolean operators: epidemiology, hepatocellular, hepatocellular cancer, hepatocellular carcinoma, unresectable, radioembolisation, selective internal radiation therapy, SIR-Spheres, yttrium 90, TACE, and sorafenib. The results were sorted or filtered by "Author", "Publication dates" or "Article types" to identify articles relevant to each section of the review. To ensure that information on ongoing clinical trials involving Y-90 resin was included, we conducted a search on "ClinicalTrials.gov", by combining the search terms "HCC" OR "hepatocellular carcinoma" with "Y 90" OR "yttrium 90" OR "radioembo", and screened for studies that involved treatment with Y-90 resin microspheres.

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